James Hagood, M.D.


Pulmonology/Respiratory Medicine


3020 Children's Way
MC 5070
San Diego, CA 92123


Pulmonology/Respiratory Medicine


Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Board Certifications

Pediatric Pulmonology, Pediatrics




Dr. Hagood is chief of the Division of Respiratory Medicine (Pulmonology) at Rady Children's Hospital-San Diego and a professor at UC San Diego School of Medicine.

He is experienced in caring for the entire spectrum of childhood breathing disorders, but his particular interest and expertise is in rare and diffuse lung diseases.

Dr. Hagood is a member of the Childhood Interstitial Lung Disease (ChILD) Research Network and an advisor to the ChILD Foundation. His laboratory studies show how normal lung air spaces develop, how scar tissue (fibrosis) forms in the lung, and how there can be new ways to treat interstitial and fibrotic lung disease.

Dr. Hagood is committed to discovering better ways to treat children with respiratory problems and to supporting their families. He believes that "everyone deserves to breathe a little easier."


Risk and impact of pulmonary complications in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.
Dietz AC, Chen Y, Yasui Y, Ness KK, Hagood JS, Chow EJ, Stovall M, Neglia JP, Oeffinger KC, Mertens AC, Robison LL, Armstrong GT, Mulrooney DA

Mechanisms of Lung Fibrosis Resolution.
Glasser SW, Hagood JS, Wong S, Taype CA, Madala SK, Hardie WD

Cigarette Smoke Enhances the Expression of Profibrotic Molecules in Alveolar Epithelial Cells.
Checa M, Hagood JS, Velazquez-Cruz R, Ruiz V, García-De-Alba C, Rangel-Escareño C, Urrea F, Becerril C, Montaño M, García-Trejo S, Cisneros Lira J, Aquino-Gálvez A, Pardo A, Selman M

Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction.
Fiore VF, Strane PW, Bryksin AV, White ES, Hagood JS, Barker TH

Diffuse Lung Disease in Biopsied Children 2 to 18 Years of Age. Application of the chILD Classification Scheme.
Fan LL, Dishop MK, Galambos C, Askin FB, White FV, Langston C, Liptzin DR, Kroehl ME, Deutsch GH, Young LR, Kurland G, Hagood J, Dell S, Trapnell BC, Deterding RR, Children’s Interstitial and Diffuse Lung Disease Research Network (chILDRN).

Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis.
Craig VJ, Zhang L, Hagood JS, Owen CA

Bronchoscopic guidance of endovascular stenting limits airway compression.
Ebrahim M, Hagood J, Moore J, El-Said H

Thy-1 modulates neurological cell-cell and cell-matrix interactions through multiple molecular interactions.
Leyton L, Hagood JS

Beyond the genome: epigenetic mechanisms in lung remodeling.
Hagood JS

Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.
Sanders YY, Hagood JS, Liu H, Zhang W, Ambalavanan N, Thannickal VJ

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE Jr, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP

Pulmonary interstitial glycogenosis in a patient ultimately diagnosed with Noonan syndrome.
Ross MK, Ellis LS, Bird LM, Hagood JS

Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.
Harris WT, Kelly DR, Zhou Y, Wang D, MacEwen M, Hagood JS, Clancy JP, Ambalavanan N, Sorscher EJ

An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy.
Kurland G, Deterding RR, Hagood JS, Young LR, Brody AS, Castile RG, Dell S, Fan LL, Hamvas A, Hilman BC, Langston C, Nogee LM, Redding GJ, American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network.

The (pediatric pulmonary) world is flat. The spread of Internet-based pediatric pulmonary case conferences.
Stokes DC, McBride JT, Hagood JS, Lesser DJ, Taylor JB

Diffuse lung disease in children: summary of a scientific conference.
Hamvas A, Deterding R, Balch WE, Schwartz DA, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS

Effect of the GPI anchor of human Thy-1 on antibody recognition and function.
Bradley JE, Chan JM, Hagood JS

Systems biology of lung development and regeneration: current knowledge and recommendations for future research.
Hagood JS, Ambalavanan N

Diffuse and interstitial lung disease and childhood rheumatologic disorders.
Dell S, Cernelc-Kohan M, Hagood JS

Hypermethylation-mediated silencing of p14(ARF) in fibroblasts from idiopathic pulmonary fibrosis.
Cisneros J, Hagood J, Checa M, Ortiz-Quintero B, Negreros M, Herrera I, Ramos C, Pardo A, Selman M

Altered DNA methylation profile in idiopathic pulmonary fibrosis.
Sanders YY, Ambalavanan N, Halloran B, Zhang X, Liu H, Crossman DK, Bray M, Zhang K, Thannickal VJ, Hagood JS

Biological insights from clinical trials and networks.
Thannickal VJ, Hagood JS

Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung.
Varisco BM, Ambalavanan N, Whitsett JA, Hagood JS

The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis.
Nuovo GJ, Hagood JS, Magro CM, Chin N, Kapil R, Davis L, Marsh CB, Folcik VA

Myofibroblast differentiation and survival in fibrotic disease.
Kis K, Liu X, Hagood JS

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.