Lori Broderick, M.D., Ph.D.


3020 Children's Way
MC 5114
San Diego, CA 92123




Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Medical School

State University of New York at Buffalo (Medicine)


University of California - San Diego


University of California - San Diego

Board Certifications

Allergy/Immunology, Pediatrics




Recurrent Fevers for the Pediatric Immunologist: It's Not All Immunodeficiency.
Broderick L

NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G

The inflammasomes and autoinflammatory syndromes.
Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E

Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy.
Yu J, Nagasu H, Murakami T, Hoang H, Broderick L, Hoffman HM, Horng T

cASCading specks.
Broderick L, Hoffman HM

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.
Brydges SD, Broderick L, McGeough MD, Pena CA, Mueller JL, Hoffman HM

Recurrent fevers and failure to thrive in an infant.
Scott DR, Chan S, Chang J, Broderick L, Hoffman HM

From NAFLD to NASH to cirrhosis-new insights into disease mechanisms.
Wree A, Broderick L, Canbay A, Hoffman HM, Feldstein AE

Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis.
Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF

Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models.
McGeough MD, Pena CA, Mueller JL, Pociask DA, Broderick L, Hoffman HM, Brydges SD

Prolonged urticaria and fever in a toddler.
Broderick L, Tremoulet AH, Burns JC, Hoffman HM

Biologic modulators in allergic and autoinflammatory diseases.
Broderick L, Tourangeau LM, Kavanaugh A, Wasserman SI

Recurrent fever syndromes in patients after recovery from Kawasaki syndrome.
Broderick L, Tremoulet AH, Burns JC, Bastian JF, Hoffman HM

Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells.
Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ Jr, Yokota SJ, Bankert RB

Membrane-associated TGF-beta1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments.
Broderick L, Bankert RB

Memory T cells in human tumor and chronic inflammatory microenvironments: sleeping beauties re-awakened by a cytokine kiss.
Broderick L, Bankert RB

Human nasal polyp microenvironment maintained in viable and functional states as xenografts in SCID mice.
Bernstein JM, Broderick L, Parsons RR, Bankert RB

IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells.
Broderick L, Brooks SP, Takita H, Baer AN, Bernstein JM, Bankert RB

Human CD4+ effector memory T cells persisting in the microenvironment of lung cancer xenografts are activated by local delivery of IL-12 to proliferate, produce IFN-gamma, and eradicate tumor cells.
Broderick L, Yokota SJ, Reineke J, Mathiowitz E, Stewart CC, Barcos M, Kelleher RJ Jr, Bankert RB

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

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