Mary Hilfiker, M.D., Ph.D.


3020 Children's Way
MC 5136
San Diego, CA 92123


Pediatric Surgery


Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Medical School

Wright State University Ohio


University of New Mexico School of Medicine


State University of New York at Buffalo GME, University of New Mexico School of Medicine


University of Maryland Medicine, University of Maryland Medicine

Board Certifications

Pediatric Surgery, Surgery




Dr. Mary Hilfiker is a pediatric surgeon and the trauma medical director at Rady Children's Hospital-San Diego. She is board certified in both general surgery and pediatric surgery.

Her philosophy of care is to educate families and understand their perspective of illness and health.

Dr. Hilfiker has been a pediatric surgeon in San Diego since 1995, when she came here after completing her training in pediatric surgery at the Children's Hospital of Buffalo. Prior to this, she attended medical school at Wright State in Dayton, Ohio, and completed her general surgery residency at the University of New Mexico in Albuquerque. Before deciding to attend medical school, she earned a Ph.D. in cell biology and conducted research at the National Institutes of Health and Cleveland Clinic in immunology. More recently, in 2009, she earned a master's in medical management at the Marshall School of Business at the University of Southern California.

Dr. Hilfiker has a strong interest in the care of injured patients and injury prevention. She is also actively involved, both regionally and nationally, in the advancement of trauma care and disaster planning.

When not at work, she enjoys horseback riding, which is "a constant learning experience, and my horse teaches me every time I ride something about life, leadership and communication." She also recently started flying lessons and is literally learning to view things from a new perspective.


Complications associated with prolonged hypertonic saline therapy in children with elevated intracranial pressure.
Gonda DD, Meltzer HS, Crawford JR, Hilfiker ML, Shellington DK, Peterson BM, Levy ML

Assessing pediatric trauma specimen integrity.
Bush RA, Mueller T, Sumwalt B, Cox SA, Hilfiker ML

A male adolescent with left iliac thrombophlebitis and heterozygosity for factor V Leiden mutation.
Lovejoy AE, Bush RA, Pong AL, Hilfiker ML

Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network.
Blakely ML, Lally KP, McDonald S, Brown RL, Barnhart DC, Ricketts RR, Thompson WR, Scherer LR, Klein MD, Letton RW, Chwals WJ, Touloukian RJ, Kurkchubasche AG, Skinner MA, Moss RL, Hilfiker ML, NEC Subcommittee of the NICHD Neonatal Research Network.

Disseminated actinomycosis presenting as a renal tumor with metastases.
Hilfiker ML

Congenital diaphragmatic hernia and chromosomal abnormalities: report of a lethal association.
Hilfiker ML, Karamanoukian HL, Hudak M, Fisher J, Glick PL

Expansion and division of conjoined twins.
Hilfiker ML, Hart M, Holmes R, Cooper M, Kriett J, Collins D, Allshouse M

Successful treatment of congenital chylous ascites with a somatostatin analogue.
Caty MG, Hilfiker ML, Azizkhan RG, Glick PL

Mycotic infections in pediatric surgical patients.
Hilfiker ML, Azizkhan RG

Fourier phase analysis of first-pass data: noninvasive detection of pulmonary sequestration.
Hilfiker ML, Telepak RJ, Jewell PF, Hartshorne MF

Allograft renal vein thrombosis in a kidney with two veins.
Hilfiker ML, Feddersen RM, Gibel LJ, Smith AY, Harford AM, Sterling WA

Interleukin 2 activity of human intestinal mucosa mononuclear cells. Decreased levels in inflammatory bowel disease.
Fiocchi C, Hilfiker ML, Youngman KR, Doerder NC, Finke JH

Endotoxin-induced T lymphocyte proliferation.
Vogel SN, Hilfiker ML, Caulfield MJ

Generation of alloreactive cytotoxic T lymphocytes: evidence for a differentiation factor distinct from IL 2.
Finke JH, Scott J, Gillis S, Hilfiker ML

In vivo development of cytolytic T lymphocytes (CTL) to hapten-altered self: MIs-disparate cells facilitate the response by neutralizing IL 2 inhibitor.
Gautam SC, Hilfiker ML, Battisto JR

Placental mononuclear phagocytes as a source of interleukin-1.
Flynn A, Finke JH, Hilfiker ML

Identification of phorbol ester receptors in T-cell growth factor-producing and -nonproducing EL4 mouse thymoma cells.
Sando JJ, Hilfiker ML, Piacentini MJ, Laufer TM

Antigen-nonspecific helper factors in the antibody response.
Farrar JJ, Hilfiker ML

The biochemistry, biology, and role of interleukin 2 in the induction of cytotoxic T cell and antibody-forming B cell responses.
Farrar JJ, Benjamin WR, Hilfiker ML, Howard M, Farrar WL, Fuller-Farrar J

Biologic properties of chromatographically separated murine thymoma-derived Interleukin 2 and colony-stimulating factor.
Hilfiker ML, Moore RN, Farrar JJ

Specific receptors for phorbol esters in lymphoid cell populations: role in enhanced production of T-cell growth factor.
Sando JJ, Hilfiker ML, Salomon DS, Farrar JJ

Phorbol myristic acetate enhances the production of interleukin 2.
Fuller-Farrar J, Hilfiker ML, Farrar WL, Farrar JJ

Thymoma production of T cell growth factor (Interleukin 2).
Farrar JJ, Fuller-Farrar J, Simon PL, Hilfiker ML, Stadler BM, Farrar WL

Macrophage-independent activation of helper T cells. I. Production of Interleukin 2.
Farrar JJ, Mizel SB, Fuller-Farrar J, Farrar WL, Hilfiker ML

In vitro production of immunosuppressive factors by murine sarcoma virus-transformed mouse fibroblasts.
Mizel SB, DeLarco JE, Todaro GJ, Farrar WL, Hilfiker ML

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.