Research and Clinical Trials

The Division focuses on outcomes research for innovative surgical procedures, clinical trials of novel treatments, and other research to better understand and improve treatments of urological and genital disorders.

Current research activities of our team members are listed below:

Nicholas Holmes, M.D.

Dr. Holmes is working with Sarah Marietti, M.D., to develop a clinical pathway to maximize the best surgical outcomes for vesicoureteral reflux. Their hope is to prevent end-stage renal disease as a result of the condition.

George Kaplan, M.D

Dr. Kaplan, the first urologist on the West Coast to exclusively practice pediatric urology, is researching surgical techniques to correct hypospadias, as well as treatment of the ureterocele complex. He has written more than 200 articles and book chapters on pediatric urology.

Madhu Alagiri, M.D., F.A.A.P.

Dr. Alagiri’s research focuses on diagnosing vesicoureteral reflux in potty-trained children using nuclear medicine scans instead of catheter-based studies. His hope is to detect urological disorders using less-invasive methods.

George Chiang, M.D.

Dr. Chiang is the principal investigator for three clinical trials at various phases involving novel medications for patients with neurogenic bladder. He is also pursuing research to evaluate advanced use of single-incision (“scarless”) techniques for a variety of pediatric urological conditions.

Additionally, he is investigating the quality of life of patients affected by spina bifida – both in the United States and in Nicaragua – as well as outcomes of patients with spinal abnormalities with regard to stone disease or complex reconstructions.