, Gastroenterology, Hepatology and Nutrition
3020 Children's Way
San Diego, CA 92123
Gastroenterology, Hepatology and Nutrition
Rady Children's Specialists of San Diego
Rady Children's Specialists
Universidad de Buenos Aires
Pediatric Gastroenterology, Pediatrics
Dr. Ariel Feldstein is chief of the Gastroenterology, Hepatology & Nutrition Division at Rady Children's Hospital-San Diego and a professor of pediatrics at UC San Diego School of Medicine.
After graduating from the Universidad de Buenos Aires Medical School and completing a postdoctoratal program in physiology at the Mayo Clinic, Dr. Feldstein went on to become the director of research for the Pediatric Institute at the Cleveland Clinic before moving to San Diego in 2011.
Dr. Feldstein oversees one of the largest pediatric gastroenterology divisions in the country, which is a top-ranked program by U.S. News & World Report. He is a renowned pediatric hepatologist who pioneered the development of non-invasive blood tests to monitor liver damage. His research is supported by several grants from the National Institutes of Health, professional associations such as the American College of Gastroenterology and pharmaceutical industry leaders. He and his lab have made significant contributions to understanding and developing therapies for obesity-associated liver disease, now the most common form of chronic liver disease in children.
Dr. Feldstein has published over 120 peer-reviewed publications in various medical journals. He currently serves as the associate editor of Seminars for Liver Disease and has held editorial positions on other gastroenterology and hepatology journals. He is a member of the Society for Pediatric Research and numerous specialty societies and has held leadership roles in the American Gastroenterological Association and the American Association for the Study of Liver Diseases.
His goal is to use his research to develop safe and effective diagnostic and therapeutic strategies for patients with highly prevalent and potentially serious conditions.
Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis.
Maricic I, Marrero I, Eguchi A, Nakamura R, Johnson CD, Dasgupta S, Hernandez CD, Nguyen PS, Swafford AD, Knight R, Feldstein AE, Loomba R, Kumar V
Correction: Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.
Alkhouri N, Johnson C, Adams L, Kitajima S, Tsuruno C, Colpitts TL, Hatcho K, Lawitz E, Lopez R, Feldstein AE
Ethanol and unsaturated dietary fat induce unique patterns of hepatic Ï‰-6 and Ï‰-3 PUFA oxylipins in a mouse model of alcoholic liver disease.
Warner DR, Liu H, Ghosh Dastidar S, Warner JB, Prodhan MAI, Yin X, Zhang X, Feldstein AE, Gao B, Prough RA, McClain CJ, Kirpich IA
Complex Network of NKT Cell Subsets Controls Immune Homeostasis in Liver and Gut.
Marrero I, Maricic I, Feldstein AE, Loomba R, Schnabl B, Rivera-Nieves J, Eckmann L, Kumar V
NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis.
Inzaugarat ME, Johnson CD, Holtmann TM, McGeough MD, Trautwein C, Papouchado BG, Schwabe R, Hoffman HM, Wree A, Feldstein AE
Liquid biopsy for liver diseases.
Mann J, Reeves HL, Feldstein AE
Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice.
Schuster S, Johnson CD, Hennebelle M, Holtmann T, Taha AY, Kirpich IA, Eguchi A, Ramsden CE, Papouchado BG, McClain CJ, Feldstein AE
Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice.
Ramsden CE, Hennebelle M, Schuster S, Keyes GS, Johnson CD, Kirpich IA, Dahlen JE, Horowitz MS, Zamora D, Feldstein AE, McClain CJ, Muhlhausler BS, Makrides M, Gibson RA, Taha AY
Triggering and resolution of inflammation in NASH.
Schuster S, Cabrera D, Arrese M, Feldstein AE
Emricasan, a pan-caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation.
Eguchi A, Koyama Y, Wree A, Johnson CD, Nakamura R, Povero D, Kneiber D, Tameda M, Contreras P, Spada A, Feldstein AE
Role of Nutrition in Alcoholic Liver Disease: Summary of the Symposium at the ESBRA 2017 Congress.
Kharbanda KK, Ronis MJJ, Shearn CT, Petersen DR, Zakhari S, Warner DR, Feldstein AE, McClain CJ, Kirpich IA
NASH-RELATED CIRRHOSIS: AN OCCULT LIVER DISEASE BURDEN.
Arrese M, Feldstein AE
TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies.
McGeough MD, Wree A, Inzaugarat ME, Haimovich A, Johnson CD, PeÃ±a CA, Goldbach-Mansky R, Broderick L, Feldstein AE, Hoffman HM
Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
Warner DR, Liu H, Miller ME, Ramsden CE, Gao B, Feldstein AE, Schuster S, McClain CJ, Kirpich IA
NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Wree A, McGeough MD, Inzaugarat ME, Eguchi A, Schuster S, Johnson CD, PeÃ±a CA, Geisler LJ, Papouchado BG, Hoffman HM, Feldstein AE
Transmembrane BAX Inhibitor motif-containing 1, a novel anti-inflammatory approach for nonalcoholic steatohepatitis treatment.
Wree A, Inzaugarat ME, Feldstein AE
Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis.
Cabrera D, Wree A, Povero D, SolÃs N, Hernandez A, Pizarro M, Moshage H, Torres J, Feldstein AE, Cabello-Verrugio C, Brandan E, Barrera F, Arab JP, Arrese M
Inflammasomes in Liver Fibrosis.
Alegre F, Pelegrin P, Feldstein AE
NASH: Novel therapeutic strategies targeting ASK1 in NASH.
Schuster S, Feldstein AE
Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?
TricÃ² D, Di Sessa A, Caprio S, Chalasani N, Liu W, Liang T, Graf J, Herzog RI, Johnson CD, Umano GR, Feldstein AE, Santoro N
Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis.
Cannito S, Morello E, Bocca C, Foglia B, Benetti E, Novo E, Chiazza F, Rogazzo M, Fantozzi R, Povero D, Sutti S, Bugianesi E, Feldstein AE, Albano E, Collino M, Parola M
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
Mridha AR, Wree A, Robertson AAB, Yeh MM, Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou GN, Masters SL, Schroder K, Cooper MA, Feldstein AE, Farrell GC
Treating nonalcoholic steatohepatitis in children: Not a cinch task.
Alkhouri N, Feldstein AE
Update on lipid species and paediatric nonalcoholic fatty liver disease.
Mann JP, Feldstein AE, Nobili V
Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress.
Eguchi A, Lazic M, Armando AM, Phillips SA, Katebian R, Maraka S, Quehenberger O, Sears DD, Feldstein AE
See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.
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