Fred Levine, M.D.

Specialty

Metabolic and Mitochondrial Medicine

Locations

3020 Children's Way
MC 5110
San Diego, CA 92123

Specialty

Metabolic and Mitochondrial Medicine

Organization

Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Publications

PAR2 regulates regeneration, transdifferentiation, and death.
Piran R, Lee SH, Kuss P, Hao E, Newlin R, Millán JL, Levine F

Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β-cell, regeneration.
Chung CH, Miller A, Panopoulos A, Hao E, Margolis R, Terskikh A, Levine F

Induction of β-cell replication by a synthetic HNF4α antagonist.
Lee SH, Piran R, Keinan E, Pinkerton A, Levine F

Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation.
Hao E, Lee SH, Levine F

Identification of alverine and benfluorex as HNF4α activators.
Lee SH, Athavankar S, Cohen T, Piran R, Kiselyuk A, Levine F

HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.
Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F

T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion.
Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ, Levine F, Ranscht B

Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells.
Lee SH, Hao E, Levine F, Itkin-Ansari P

β-Cell replication and islet neogenesis following partial pancreatectomy.
Lee SH, Hao E, Levine F

The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.
Lee SH, Hao E, Kiselyuk A, Shapiro J, Shields DJ, Lowy A, Levine F, Itkin-Ansari P

CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells.
Lee SH, Itkin-Ansari P, Levine F

Adult pancreatic alpha-cells: a new source of cells for beta-cell regeneration.
Chung CH, Levine F

Pancreatic β-cell neogenesis by direct conversion from mature α-cells.
Chung CH, Hao E, Piran R, Keinan E, Levine F

Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen.
Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F

Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Zhang SS, Hao E, Yu J, Liu W, Wang J, Levine F, Feng GS

Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.
Dawson MI, Ye M, Cao X, Farhana L, Hu QY, Zhao Y, Xu LP, Kiselyuk A, Correa RG, Yang L, Hou T, Reed JC, Itkin-Ansari P, Levine F, Sanner MF, Fontana JA, Zhang XK

Islet specific Wnt activation in human type II diabetes.
Lee SH, Demeterco C, Geron I, Abrahamsson A, Levine F, Itkin-Ansari P

beta-cell Regeneration: neogenesis, replication or both?
Levine F, Itkin-Ansari P

HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F

Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.
Katkov II, Kim MS, Bajpai R, Altman YS, Mercola M, Loring JF, Terskikh AV, Snyder EY, Levine F

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.
Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, Levine F

Telomere-independent cellular senescence in human fetal cardiomyocytes.
Ball AJ, Levine F

Chronic treatment of mitochondrial disease patients with dichloroacetate.
Barshop BA, Naviaux RK, McGowan KA, Levine F, Nyhan WL, Loupis-Geller A, Haas RH

No pancreatic endocrine stem cells?
Levine F, Mercola M

Sources of beta-cells for human cell-based therapies for diabetes.
Itkin-Ansari P, Levine F

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.