Metabolic and Mitochondrial Medicine
Rady Children's Specialists of San Diego
Rady Children's Specialists
High-throughput screening and bioinformatic analysis to ascertain compounds that prevent saturated fatty acid-induced Î²-cell apoptosis.
Lee SH, Cunha D, Piermarocchi C, Paternostro G, Pinkerton A, Ladriere L, Marchetti P, Eizirik DL, Cnop M, Levine F
PAR2 regulates regeneration, transdifferentiation, and death.
Piran R, Lee SH, Kuss P, Hao E, Newlin R, MillÃ¡n JL, Levine F
Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not Î²-cell, regeneration.
Chung CH, Miller A, Panopoulos A, Hao E, Margolis R, Terskikh A, Levine F
Induction of Î²-cell replication by a synthetic HNF4Î± antagonist.
Lee SH, Piran R, Keinan E, Pinkerton A, Levine F
Identification of alverine and benfluorex as HNF4Î± activators.
Lee SH, Athavankar S, Cohen T, Piran R, Kiselyuk A, Levine F
HNF4Î± antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.
Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F
T-cadherin (Cdh13) in association with pancreatic Î²-cell granules contributes to second phase insulin secretion.
Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ, Levine F, Ranscht B
Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic Î²-cells.
Lee SH, Hao E, Levine F, Itkin-Ansari P
Î²-Cell replication and islet neogenesis following partial pancreatectomy.
Lee SH, Hao E, Levine F
The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.
Lee SH, Hao E, Kiselyuk A, Shapiro J, Shields DJ, Lowy A, Levine F, Itkin-Ansari P
CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells.
Lee SH, Itkin-Ansari P, Levine F
Pancreatic Î²-cell neogenesis by direct conversion from mature Î±-cells.
Chung CH, Hao E, Piran R, Keinan E, Levine F
Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen.
Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F
Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells.
Zhang SS, Hao E, Yu J, Liu W, Wang J, Levine F, Feng GS
Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.
Dawson MI, Ye M, Cao X, Farhana L, Hu QY, Zhao Y, Xu LP, Kiselyuk A, Correa RG, Yang L, Hou T, Reed JC, Itkin-Ansari P, Levine F, Sanner MF, Fontana JA, Zhang XK
Islet specific Wnt activation in human type II diabetes.
Lee SH, Demeterco C, Geron I, Abrahamsson A, Levine F, Itkin-Ansari P
beta-cell Regeneration: neogenesis, replication or both?
Levine F, Itkin-Ansari P
HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F
Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.
Katkov II, Kim MS, Bajpai R, Altman YS, Mercola M, Loring JF, Terskikh AV, Snyder EY, Levine F
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.
Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, Levine F
Chronic treatment of mitochondrial disease patients with dichloroacetate.
Barshop BA, Naviaux RK, McGowan KA, Levine F, Nyhan WL, Loupis-Geller A, Haas RH
No pancreatic endocrine stem cells?
Levine F, Mercola M
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