Gabriel Haddad, M.D.


Pulmonology/Respiratory Medicine


3020 Children's Way
MC 5109
San Diego, CA 92123


Pulmonology/Respiratory Medicine


Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Board Certifications

Pulmonology/Respiratory Medicine




Dr. Gabriel G. Haddad is physician-in-chief and chief scientific officer at Rady Children's Hospital-San Diego and chairman of the Department of Pediatrics at UC San Diego School of Medicine. A leading specialist in pediatric respiratory medicine, he is also an accomplished physician-scientist.

Receiving his medical education and initial medical training at the American University of Beirut in Lebanon, Dr. Haddad went on to complete additional training at the University of Texas in Houston, followed by a fellowship at Columbia University in New York, where he joined the faculty in 1978. A decade later, he accepted an appointment at Yale to direct the Respiratory Medicine Section and serve as chief of clinical service in respiratory medicine. Shortly thereafter, he became a professor of cellular & molecular physiology. In 2002, he was appointed chairman of the Department of Pediatrics at Albert Einstein College of Medicine in New York and also pediatrician-in-chief at The Children's Hospital at Montefiore Hospital.

Dr. Haddad is passionate about developing better care through research. In recent years, his research has focused on the basis for cell and tissue injury at the molecular level when tissues and organs are deprived of nutrients and oxygen.

Dr. Haddad has published more than 230 articles and manuscripts, written more than 100 chapters, and authored numerous medical texts including the landmark "Basic Mechanisms of Pediatric Respiratory Disease." He sits on numerous national committees, including those of the National Heart, Lung and Blood Institute and March of Dimes, and is a member of 18 distinguished medical societies, many in a leadership role.

Additionally, Dr. Haddad has held numerous editorial appointments, is a reviewer for 29 respected medical journals and is the recipient of numerous awards and honors, including election into the Association of American Physicians. He has been invited to speak at more than 160 national and international conferences and is also a member of the St. Jude Children's Research Hospital Board of Governors.

Dr. Haddad is married and the father of three children, a daughter and two sons.


Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease.
Azad P, Zhao HW, Cabrales PJ, Ronen R, Zhou D, Poulsen O, Appenzeller O, Hsiao YH, Bafna V, Haddad GG

The Na<sup>+</sup>/HCO<sub>3</sub><sup>-</sup> co-transporter is protective during ischemia in astrocytes.
Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad GG

Intermittent hypoxia induces murine macrophage foam cell formation by IKK-β-dependent NF-κB pathway activation.
Imamura T, Poulsen O, Haddad GG

Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits.
Aggarwal DD, Rashkovetsky E, Michalak P, Cohen I, Ronin Y, Zhou D, Haddad GG, Korol AB

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations.
Jha AR, Zhou D, Brown CD, Kreitman M, Haddad GG, White KP

Cardiac responses to hypoxia and reoxygenation in Drosophila.
Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K

Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice.
Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG

Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism.
Manchenkov T, Pasillas MP, Haddad GG, Imam FB

Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX

A Drosophila ABC transporter regulates lifespan.
Huang H, Lu-Bo Y, Haddad GG

High-throughput cell death assays.
Pamenter ME, Haddad GG

The genetic basis of chronic mountain sickness.
Ronen R, Zhou D, Bafna V, Haddad GG

Hematopoietic stem cells: potential new applications for translational medicine.
Felfly H, Haddad GG

Wnt pathway activation increases hypoxia tolerance during development.
Gersten M, Zhou D, Azad P, Haddad GG, Subramaniam S

Do BK channels mediate glioma hypoxia-tolerance?
Pamenter ME, Haddad GG

MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data.
Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC

Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster.
Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes.
Udpa N, Ronen R, Zhou D, Liang J, Stobdan T, Appenzeller O, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Claydon VE, Hainsworth R, Gamboa JL, Zibenigus M, Zenebe G, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG

Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma.
Gu XQ, Pamenter ME, Siemen D, Sun X, Haddad GG

Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures.
Hartley I, Elkhoury FF, Heon Shin J, Xie B, Gu X, Gao Y, Zhou D, Haddad GG

Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions.
Yin S, Xue J, Sun H, Wen B, Wang Q, Perkins G, Zhao HW, Ellisman MH, Hsiao YH, Yin L, Xie Y, Hou G, Zi J, Lin L, Haddad GG, Zhou D, Liu S

Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice.
Douglas RM, Bowden K, Pattison J, Peterson AB, Juliano J, Dalton ND, Gu Y, Alvarez E, Imamura T, Peterson KL, Witztum JL, Haddad GG, Li AC

Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders.
Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao HW, Yin Y, Du Y, Guo L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa JL, Villafuerte F, Callacondo D, Xue J, Liu S, Frazer KA, Li Y, Bafna V, Haddad GG

Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia.
Xie L, Ng C, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad GG, Bourne PE, Xie L

Chemokine receptor-like 2 is involved in ischemic brain injury.
Douglas RM, Chen AH, Iniguez A, Wang J, Fu Z, Powell FL Jr, Haddad GG, Yao H

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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