3020 Children's Way
MC 5137
San Diego, CA 92123




Rady Children's Specialists of San Diego

Medical Group / IPA


Medical School

University of Hong Kong, University of London


Guy's Hospital Medical School, Queen Elizabeth Hospital of Hong Kong


Guys and St Thomas Hospital NHS Trust, Karlsruhe Hospital, Yale University School of Medicine




Dr. Robert Mak is chief of the Pediatric Nephrology Division at Rady Children's Hospital-San Diego and a tenured professor of pediatrics at UC San Diego.

He completed a pediatric residency and pediatric nephrology fellowship at Guy's Hospital Medical School. He also received his PhD in pediatric nephrology at University of London before enrolling in postdoctoral research training at Yale University and Heidelberg University. He was a faculty member at Stanford University, University of Southern California and Oregon Health and Science University before joining UC San Diego.

Dr. Mak has served as council representing the United States and chair of the global education committee for the International Pediatric Nephrology Association. He participated in several study sections at the National Institute of Health. He co-founded and served as president of the Western Society of Pediatric Nephrology. He is also on the editorial board for several medical journals, including Nature Reviews Nephrology, World Journal of Pediatrics, World Journal of Nephrology and World Journal of Hypertension.

His research interests include energy homeostasis, bone-mineral and cardiovascular complications as well as mechanisms of progression in chronic kidney disease. His laboratory is studying the molecular mechanism of cachexia associated with chronic kidney disease using rodent models. He has served on and chaired committees for a wide variety of research projects and clinical trials. He has also trained many postdoctoral fellows who in the past three years have won several regional and national scientific research awards from societies such as the Western Society of Pediatric Nephrology, American Society of Pediatric Nephrology and the Pediatric Academic Societies of the United States.


Vitamin D ameliorates adipose browning in chronic kidney disease cachexia.
Cheung WW, Ding W, Hoffman HM, Wang Z, Hao S, Zheng R, Gonzalez A, Zhan JY, Zhou P, Li S, Esparza MC, Lieber RL, Mak RH

Editorial: Developmental Disorders of the Kidney and Urinary Tract: Recent Insights From Clinical and Molecular Studies.
Oliveira EA, Mak RH, Simões E Silva AC

Use of Simulation Strategies to Predict Subtherapeutic Meropenem Exposure Caused by Augmented Renal Clearance in Critically Ill Pediatric Patients With Sepsis.
Avedissian SN, Skochko SM, Le J, Hingtgen S, Harvey H, Capparelli EV, Richardson A, Momper J, Mak RH, Neely M, Bradley JS

Microvascular disease in chronic kidney disease: the base of the iceberg in cardiovascular comorbidity.
Querfeld U, Mak RH, Pries AR

Low Serum Bicarbonate and CKD Progression in Children.
Brown DD, Roem J, Ng DK, Reidy KJ, Kumar J, Abramowitz MK, Mak RH, Furth SL, Schwartz GJ, Warady BA, Kaskel FJ, Melamed ML

Urinary tract infection in pediatrics: an overview.
Simões E Silva AC, Oliveira EA, Mak RH

Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis-associated cachexia.
Cheung WW, Hao S, Wang Z, Ding W, Zheng R, Gonzalez A, Zhan JY, Zhou P, Li S, Esparza MC, Hoffman HM, Lieber RL, Mak RH

Cachexia/Protein energy wasting syndrome in CKD: Causation and treatment.
Oliveira EA, Zheng R, Carter CE, Mak RH

A Predictive Model of Postnatal Surgical Intervention in Children With Prenatally Detected Congenital Anomalies of the Kidney and Urinary Tract.
Vasconcelos MA, Oliveira EA, Simões E Silva AC, Dias CS, Mak RH, Fonseca CC, Campos APM, Steyerberg EW, Vergouwe Y

Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis.
Lobry T, Miller R, Nevo N, Rocca CJ, Zhang J, Catz SD, Moore F, Thomas L, Pouly D, Bailleux A, Guerrera IC, Gubler MC, Cheung WW, Mak RH, Montier T, Antignac C, Cherqui S

A clinical predictive model of renal injury in children with congenital solitary functioning kidney.
Poggiali IV, Simões E Silva AC, Vasconcelos MA, Dias CS, Gomes IR, Carvalho RA, Oliveira MCL, Pinheiro SV, Mak RH, Oliveira EA

A clinical predictive model of chronic kidney disease in children with posterior urethral valves.
Vasconcelos MA, E Silva ACS, Gomes IR, Carvalho RA, Pinheiro SV, Colosimo EA, Yorgin P, Mak RH, Oliveira EA

Unacylated ghrelin and obestatin in pediatric CKD: are they important in protein energy wasting?
Wang Z, Oliveira EA, Mak RH

Progression of chronic kidney disease in children - role of glomerular hemodynamics and interstitial fibrosis.
Oliveira EA, Mak RH

Steroid-resistant nephrotic syndrome: past and current perspectives.
Nourbakhsh N, Mak RH

Preparation of Potent Leptin Receptor Antagonists and Their Therapeutic Use in Mouse Models of Uremic Cachexia and Kidney Fibrosis.
Mak RH, Cheung WW, Solomon G, Gertler A

Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study.
Ku E, Kopple JD, McCulloch CE, Warady BA, Furth SL, Mak RH, Grimes BA, Mitsnefes M

MicroRNA as Novel Exercise Mimetic for Muscle Wasting in CKD.
Mak RH, Cheung WW

Emerging roles of nuclear phosphatase SCP4 in CKD-associated muscle wasting.
Cheung WW, Hao S, Mak RH

Albuminuria, Proteinuria, and Renal Disease Progression in Children with CKD.
Fuhrman DY, Schneider MF, Dell KM, Blydt-Hansen TD, Mak R, Saland JM, Furth SL, Warady BA, Moxey-Mims MM, Schwartz GJ

Muscle wasting in chronic kidney disease.
Oliveira EA, Cheung WW, Toma KG, Mak RH

Cachexia in children with chronic kidney disease: challenges in diagnosis and treatment.
Mak RH

Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis.
Cheung WW, Cherqui S, Ding W, Esparza M, Zhou P, Shao J, Lieber RL, Mak RH

Inflammation and nutrition in children with chronic kidney disease.
Tu J, Cheung WW, Mak RH

Evaluation and management of hydronephrosis in the neonate.
Oliveira EA, Oliveira MC, Mak RH

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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