Robert Mak, M.D., Ph.D.

Bio

Dr. Robert Mak is chief of the Pediatric Nephrology Division at Rady Children's Hospital-San Diego and a tenured professor of pediatrics at UC San Diego.

He completed a pediatric residency and pediatric nephrology fellowship at Guy's Hospital Medical School. He also received his PhD in pediatric nephrology at University of London before enrolling in postdoctoral research training at Yale University and Heidelberg University. He was a faculty member at Stanford University, University of Southern California and Oregon Health and Science University before joining UC San Diego.

Dr. Mak has served as council representing the United States and chair of the global education committee for the International Pediatric Nephrology Association. He participated in several study sections at the National Institute of Health. He co-founded and served as president of the Western Society of Pediatric Nephrology. He is also on the editorial board for several medical journals, including Nature Reviews Nephrology, World Journal of Pediatrics, World Journal of Nephrology and World Journal of Hypertension.

His research interests include energy homeostasis, bone-mineral and cardiovascular complications as well as mechanisms of progression in chronic kidney disease. His laboratory is studying the molecular mechanism of cachexia associated with chronic kidney disease using rodent models. He has served on and chaired committees for a wide variety of research projects and clinical trials. He has also trained many postdoctoral fellows who in the past three years have won several regional and national scientific research awards from societies such as the Western Society of Pediatric Nephrology, American Society of Pediatric Nephrology and the Pediatric Academic Societies of the United States.

Publications

Effectiveness of BNT162b2 and CoronaVac vaccines against omicron in children aged 5 to 11 years.
Oliveira EA, Oliveira MCL, Silva ACSE, Colosimo EA, Mak RH, Vasconcelos MA, Silva LR, Martelli DB, Pinhati CC, Martelli-Júnior H

Nutrition in Children With Chronic Kidney Disease: How to Thrive?
Mak RH, Iyengar A, Lai WM, McAlister L, Oliveira EA, Xu H, Yap HK, Shroff R

Is There a Need to "Modernize" and "Simplify" the Diagnostic Criteria of Protein-Energy Wasting?
Koppe L, Mak RH

Association of Prior COVID-19 Vaccination With SARS-CoV-2 Infection and Death in Children and Young Persons During the Omicron Variant Period in Brazil.
Oliveira EA, Oliveira MCL, Simões E Silva AC, Colosimo EA, Mak RH, Pinhati CC, Martelli H Jr

Redox Signaling in Chronic Kidney Disease-Associated Cachexia.
Simões E Silva AC, Oliveira EA, Cheung WW, Mak RH

Maternal risk factors for congenital anomalies of the kidney and urinary tract: A case-control study.
Boato RT, Aguiar MB, Mak RH, Colosimo EA, Simões E Silva AC, Oliveira EA

Clinical Impact and Risk Factors of Mortality in Hospitalized Children and Adolescents With Hematologic Diseases and COVID-19: An Observational Retrospective Cohort Study.
Oliveira MCL, Simões E Silva AC, Colosimo EA, Campos MK, Martelli-Júnior H, Silva LR, Pinhati CC, Mak RH, Oliveira EA

Clinical Outcomes of Omicron Variant (B.1.1.529) Infection in Children and Adolescents Hospitalized With COVID-19 in Brazil With Observational Data on the Efficacy of the Vaccines in Adolescents.
Oliveira EA, Oliveira MCL, Silva ACSE, Colosimo EA, Mak RH, Vasconcelos MA, Silva LR, Martelli DB, Pinhati CC, Martelli-Júnior H

The association between pre-existing asthma and reduced risk of death among children and adolescents hospitalized with COVID-19 in Brazil.
Oliveira MCL, Colosimo EA, Vasconcelos MA, Martelli-Júnior H, Mak RH, Silva LR, Pinhati CC, Simões E Silva AC, Oliveira EA

Vaccine Effectiveness against SARS-CoV-2 Variants in Adolescents from 15 to 90 Days after Second Dose: A Population-Based Test-Negative Case-Control Study.
Oliveira EA, Oliveira MCL, Colosimo EA, Simões E Silva AC, Mak RH, Vasconcelos MA, Silva LR, Martelli DB, Pinhati CC, Martelli-Júnior H

Outcomes and risk factors for death among hospitalized children and adolescents with kidney diseases and COVID-19: an analysis of a nationwide database.
Vasconcelos MA, Mendonça ACQ, Colosimo EA, Nourbakhsh N, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Mak RH, Simões E Silva AC, Oliveira EA

Growth Hormone Improves Adipose Tissue Browning and Muscle Wasting in Mice with Chronic Kidney Disease-Associated Cachexia.
Mak RH, Gunta S, Oliveira EA, Cheung WW

Metabolic Advantage of 25(OH)D(3) versus 1,25(OH)(2)D(3) Supplementation in Infantile Nephropathic Cystinosis-Associated Adipose Tissue Browning and Muscle Wasting.
Zhou P, Cheung WW, Gonzalez A, Vaddi V, Oliveira EA, Mak RH

Outcomes and risk factors of death among hospitalized children and adolescents with obesity and COVID-19 in Brazil: An analysis of a nationwide database.
Simões E Silva AC, Vasconcelos MA, Colosimo EA, Mendonça ACQ, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Mak RH, Oliveira EA

Risk factors for COVID-19-related mortality in hospitalized children and adolescents with diabetes mellitus: An observational retrospective cohort study.
Oliveira EA, Mak RH, Colosimo EA, Mendonça ACQ, Vasconcelos MA, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Simões E Silva AC

n-3 PUFA dietary lipid replacement normalizes muscle mitochondrial function and oxidative stress through enhanced tissue mitophagy and protects from muscle wasting in experimental kidney disease.
Gortan Cappellari G, Semolic A, Ruozi G, Barbetta D, Bortolotti F, Vinci P, Zanetti M, Mak RH, Garibotto G, Giacca M, Barazzoni R

Assessment of Undernutrition in Pediatric Chronic Kidney Disease - Gaps and Opportunities.
Iyengar A, Mak RH

Comparison of the First and Second Waves of the Coronavirus Disease 2019 Pandemic in Children and Adolescents in a Middle-Income Country: Clinical Impact Associated with Severe Acute Respiratory Syndrome Coronavirus 2 Gamma Lineage.
Oliveira EA, Simões E Silva AC, Oliveira MCL, Colosimo EA, Mak RH, Vasconcelos MA, Miranda DM, Martelli DB, Silva LR, Pinhati CC, Martelli-Júnior H

Postnatal urinary tract dilatation classification: improvement of the accuracy in predicting kidney injury.
Melo FF, Vasconcelos MA, Mak RH, Silva ACSE, Dias CS, Colosimo EA, Silva LR, Oliveira MCL, Oliveira EA

Activin A Signaling Provides an Interorgan Link Between Kidney and Muscle in CKD-Associated Muscle Wasting.
Perens EA, Hoffman HM, Mak RH

Differential Effects of 25-Hydroxyvitamin D(3) versus 1α 25-Dihydroxyvitamin D(3) on Adipose Tissue Browning in CKD-Associated Cachexia.
Mak RH, Querfeld U, Gonzalez A, Gunta S, Cheung WW

Risk factors for COVID-19 mortality in hospitalised children and adolescents in Brazil - Authors' reply.
Oliveira EA, Colosimo EA, E Silva ACS, Mak RH, Martelli DB, Silva LR, Martelli-Júnior H, Oliveira MCL

Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis.
Cheung WW, Hao S, Zheng R, Wang Z, Gonzalez A, Zhou P, Hoffman HM, Mak RH

Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort Study.
Melo FF, Mak RH, Simões E Silva AC, Vasconcelos MA, Dias CS, Rosa LC, Shiomatsu GY, Storch C, Oliveira MCL, Oliveira EA

Preliminary assessment of cavity-nesting Hymenopterans in a low-intensity agricultural landscape in Transylvania.
Lajos K, Demeter I, Mák R, Balog A, Sárospataki M

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

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