San Diego County

3020 Children's Way
MC 5137
San Diego, CA 92123




Rady Children's Specialists of San Diego

Medical Group / IPA


Medical School

University of Hong Kong, University of London


Guy's Hospital Medical School, Queen Elizabeth Hospital of Hong Kong


Guys and St Thomas Hospital NHS Trust, Karlsruhe Hospital, Yale University School of Medicine




Dr. Robert Mak is chief of the Pediatric Nephrology Division at Rady Children's Hospital-San Diego and a tenured professor of pediatrics at UC San Diego.

He completed a pediatric residency and pediatric nephrology fellowship at Guy's Hospital Medical School. He also received his PhD in pediatric nephrology at University of London before enrolling in postdoctoral research training at Yale University and Heidelberg University. He was a faculty member at Stanford University, University of Southern California and Oregon Health and Science University before joining UC San Diego.

Dr. Mak has served as council representing the United States and chair of the global education committee for the International Pediatric Nephrology Association. He participated in several study sections at the National Institute of Health. He co-founded and served as president of the Western Society of Pediatric Nephrology. He is also on the editorial board for several medical journals, including Nature Reviews Nephrology, World Journal of Pediatrics, World Journal of Nephrology and World Journal of Hypertension.

His research interests include energy homeostasis, bone-mineral and cardiovascular complications as well as mechanisms of progression in chronic kidney disease. His laboratory is studying the molecular mechanism of cachexia associated with chronic kidney disease using rodent models. He has served on and chaired committees for a wide variety of research projects and clinical trials. He has also trained many postdoctoral fellows who in the past three years have won several regional and national scientific research awards from societies such as the Western Society of Pediatric Nephrology, American Society of Pediatric Nephrology and the Pediatric Academic Societies of the United States.


Clinical Impact and Risk Factors of Mortality in Hospitalized Children and Adolescents With Hematological Diseases and COVID-19: An Observational Retrospective Cohort Study.
Oliveira MCL, Simões E Silva AC, Colosimo EA, Campos MK, Martelli-Júnior H, Silva LR, Pinhati CC, Mak RH, Oliveira EA

n-3 PUFA dietary lipid replacement normalizes muscle mitochondrial function and oxidative stress through enhanced tissue mitophagy and protects from muscle wasting in experimental kidney disease.
Gortan Cappellari G, Semolic A, Ruozi G, Barbetta D, Bortolotti F, Vinci P, Zanetti M, Mak RH, Garibotto G, Giacca M, Barazzoni R

Assessment of Undernutrition in Pediatric Chronic Kidney Disease - Gaps and Opportunities.
Iyengar A, Mak RH

Outcomes and risk factors for death among hospitalized children and adolescents with kidney diseases and COVID-19: an analysis of a nationwide database.
Vasconcelos MA, Mendonça ACQ, Colosimo EA, Nourbakhsh N, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Mak RH, Simões E Silva AC, Oliveira EA

Outcomes and risk factors of death among hospitalized children and adolescents with obesity and COVID-19 in Brazil: An analysis of a nationwide database.
Simões E Silva AC, Vasconcelos MA, Colosimo EA, Mendonça ACQ, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Mak RH, Oliveira EA

Risk factors for COVID-19-related mortality in hospitalized children and adolescents with diabetes mellitus: An observational retrospective cohort study.
Oliveira EA, Mak RH, Colosimo EA, Mendonça ACQ, Vasconcelos MA, Martelli-Júnior H, Silva LR, Oliveira MCL, Pinhati CC, Simões E Silva AC

Comparison of the First and Second Waves of the Coronavirus Disease 2019 Pandemic in Children and Adolescents in a Middle-Income Country: Clinical Impact Associated with Severe Acute Respiratory Syndrome Coronavirus 2 Gamma Lineage.
Oliveira EA, Simões E Silva AC, Oliveira MCL, Colosimo EA, Mak RH, Vasconcelos MA, Miranda DM, Martelli DB, Silva LR, Pinhati CC, Martelli-Júnior H

Differential Effects of 25-Hydroxyvitamin D3 versus 1α 25-Dihydroxyvitamin D3 on Adipose Tissue Browning in CKD-Associated Cachexia.
Mak RH, Querfeld U, Gonzalez A, Gunta S, Cheung WW

Activin A Signaling Provides an Interorgan Link Between Kidney and Muscle in CKD-Associated Muscle Wasting.
Perens EA, Hoffman HM, Mak RH

Risk factors for COVID-19 mortality in hospitalised children and adolescents in Brazil - Authors' reply.
Oliveira EA, Colosimo EA, E Silva ACS, Mak RH, Martelli DB, Silva LR, Martelli-Júnior H, Oliveira MCL

Preliminary assessment of cavity-nesting Hymenopterans in a low-intensity agricultural landscape in Transylvania.
Lajos K, Demeter I, Mák R, Balog A, Sárospataki M

Postnatal urinary tract dilatation classification: improvement of the accuracy in predicting kidney injury.
Melo FF, Vasconcelos MA, Mak RH, Silva ACSE, Dias CS, Colosimo EA, Silva LR, Oliveira MCL, Oliveira EA

A Leptin Receptor Antagonist Attenuates Adipose Tissue Browning and Muscle Wasting in Infantile Nephropathic Cystinosis-Associated Cachexia.
Gonzalez A, Cheung WW, Perens EA, Oliveira EA, Gertler A, Mak RH

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia.
Cheung WW, Zheng R, Hao S, Wang Z, Gonzalez A, Zhou P, Hoffman HM, Mak RH

Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis.
Cheung WW, Hao S, Zheng R, Wang Z, Gonzalez A, Zhou P, Hoffman HM, Mak RH

The Role of Growth Hormone in Chronic Kidney Disease.
Oliveira EA, Carter CE, Mak RH

Clinical characteristics and risk factors for death among hospitalised children and adolescents with COVID-19 in Brazil: an analysis of a nationwide database.
Oliveira EA, Colosimo EA, Simões E Silva AC, Mak RH, Martelli DB, Silva LR, Martelli-Júnior H, Oliveira MCL

Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort Study.
Melo FF, Mak RH, Simões E Silva AC, Vasconcelos MA, Dias CS, Rosa LC, Shiomatsu GY, Storch C, Oliveira MCL, Oliveira EA

Standardized urine biomarkers in assessing neonatal kidney function: are we there yet?
Mak RH, Abitbol CL

Vitamin D ameliorates adipose browning in chronic kidney disease cachexia.
Cheung WW, Ding W, Hoffman HM, Wang Z, Hao S, Zheng R, Gonzalez A, Zhan JY, Zhou P, Li S, Esparza MC, Lieber RL, Mak RH

Editorial: Developmental Disorders of the Kidney and Urinary Tract: Recent Insights From Clinical and Molecular Studies.
Oliveira EA, Mak RH, Simões E Silva AC

Use of Simulation Strategies to Predict Subtherapeutic Meropenem Exposure Caused by Augmented Renal Clearance in Critically Ill Pediatric Patients With Sepsis.
Avedissian SN, Skochko SM, Le J, Hingtgen S, Harvey H, Capparelli EV, Richardson A, Momper J, Mak RH, Neely M, Bradley JS

Microvascular disease in chronic kidney disease: the base of the iceberg in cardiovascular comorbidity.
Querfeld U, Mak RH, Pries AR

Low Serum Bicarbonate and CKD Progression in Children.
Brown DD, Roem J, Ng DK, Reidy KJ, Kumar J, Abramowitz MK, Mak RH, Furth SL, Schwartz GJ, Warady BA, Kaskel FJ, Melamed ML

Urinary tract infection in pediatrics: an overview.
Simões E Silva AC, Oliveira EA, Mak RH

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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