Robert Mak, M.D., Ph.D.

Locations

3020 Children's Way
MC 5137
San Diego, CA 92123

Specialty

Nephrology

Organization

Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Medical School

University of Hong Kong, University of London

Residency

Guy's Hospital Medical School, Queen Elizabeth Hospital of Hong Kong

Fellowship

Guys and St Thomas Hospital NHS Trust, Karlsruhe Hospital, Yale University School of Medicine

Gender

M

Bio

Dr. Robert Mak is chief of the Pediatric Nephrology Division at Rady Children's Hospital-San Diego and a tenured professor of pediatrics at UC San Diego.

He completed a pediatric residency and pediatric nephrology fellowship at Guy's Hospital Medical School. He also received his PhD in pediatric nephrology at University of London before enrolling in postdoctoral research training at Yale University and Heidelberg University. He was a faculty member at Stanford University, University of Southern California and Oregon Health and Science University before joining UC San Diego.

Dr. Mak has served as council representing the United States and chair of the global education committee for the International Pediatric Nephrology Association. He participated in several study sections at the National Institute of Health. He co-founded and served as president of the Western Society of Pediatric Nephrology. He is also on the editorial board for several medical journals, including Nature Reviews Nephrology, World Journal of Pediatrics, World Journal of Nephrology and World Journal of Hypertension.

His research interests include energy homeostasis, bone-mineral and cardiovascular complications as well as mechanisms of progression in chronic kidney disease. His laboratory is studying the molecular mechanism of cachexia associated with chronic kidney disease using rodent models. He has served on and chaired committees for a wide variety of research projects and clinical trials. He has also trained many postdoctoral fellows who in the past three years have won several regional and national scientific research awards from societies such as the Western Society of Pediatric Nephrology, American Society of Pediatric Nephrology and the Pediatric Academic Societies of the United States.

Publications

A clinical predictive model of renal injury in children with congenital solitary functioning kidney.
Poggiali IV, Simões E Silva AC, Vasconcelos MA, Dias CS, Gomes IR, Carvalho RA, Oliveira MCL, Pinheiro SV, Mak RH, Oliveira EA

A clinical predictive model of chronic kidney disease in children with posterior urethral valves.
Vasconcelos MA, E Silva ACS, Gomes IR, Carvalho RA, Pinheiro SV, Colosimo EA, Yorgin P, Mak RH, Oliveira EA

Unacylated ghrelin and obestatin in pediatric CKD: are they important in protein energy wasting?
Wang Z, Oliveira EA, Mak RH

Progression of chronic kidney disease in children - role of glomerular hemodynamics and interstitial fibrosis.
Oliveira EA, Mak RH

Steroid-resistant nephrotic syndrome: past and current perspectives.
Nourbakhsh N, Mak RH

Preparation of Potent Leptin Receptor Antagonists and Their Therapeutic Use in Mouse Models of Uremic Cachexia and Kidney Fibrosis.
Mak RH, Cheung WW, Solomon G, Gertler A

Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study.
Ku E, Kopple JD, McCulloch CE, Warady BA, Furth SL, Mak RH, Grimes BA, Mitsnefes M

MicroRNA as Novel Exercise Mimetic for Muscle Wasting in CKD.
Mak RH, Cheung WW

Emerging roles of nuclear phosphatase SCP4 in CKD-associated muscle wasting.
Cheung WW, Hao S, Mak RH

Albuminuria, Proteinuria, and Renal Disease Progression in Children with CKD.
Fuhrman DY, Schneider MF, Dell KM, Blydt-Hansen TD, Mak R, Saland JM, Furth SL, Warady BA, Moxey-Mims MM, Schwartz GJ

Muscle wasting in chronic kidney disease.
Oliveira EA, Cheung WW, Toma KG, Mak RH

Cachexia in children with chronic kidney disease: challenges in diagnosis and treatment.
Mak RH

Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis.
Cheung WW, Cherqui S, Ding W, Esparza M, Zhou P, Shao J, Lieber RL, Mak RH

Inflammation and nutrition in children with chronic kidney disease.
Tu J, Cheung WW, Mak RH

Evaluation and management of hydronephrosis in the neonate.
Oliveira EA, Oliveira MC, Mak RH

Nephrology research--the past, present and future.
Floege J, Mak RH, Molitoris BA, Remuzzi G, Ronco P

Transplantation: Outcomes of prenatal immunosuppression.
Mak RH, Hoffman HM

Impact of obesity on kidney function and blood pressure in children.
Ding W, Cheung WW, Mak RH

Predictors of Rapid Progression of Glomerular and Nonglomerular Kidney Disease in Children and Adolescents: The Chronic Kidney Disease in Children (CKiD) Cohort.
Warady BA, Abraham AG, Schwartz GJ, Wong CS, Muñoz A, Betoko A, Mitsnefes M, Kaskel F, Greenbaum LA, Mak RH, Flynn J, Moxey-Mims MM, Furth S

Nephrotic syndrome: Efficacy of rituximab in challenging nephrotic syndrome.
Lemley KV, Mak RH

Early markers of obesity-related renal injury in childhood.
Ding W, Mak RH

Exploiting the therapeutic potential of leptin signaling in cachexia.
Mak RH, Cheung WW, Gertler A

Chronic kidney disease: Prenatal risk factors for kidney and urinary tract anomalies.
Mak RH, Schaefer F

C/EBPα regulates macrophage activation and systemic metabolism.
Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J

Growth in children with chronic kidney disease: role of nutrition, growth hormone, dialysis, and steroids.
Ingulli EG, Mak RH

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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