Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms
Acid Alpha-Glucosidase; Acid Maltase Deficiency; Alpha-Glucosidase Deficiency; Glycogen Storage Disease Type II (GSD II); Pompe Disease
Specimen Type
Whole Blood
Performing Lab
Mayo Medical Lab
Epic ID
Other Reference Test
Lab Test Days
Monday and Wednesday
Standard TAT
3-7- Days
Collection Information
Specimen Required
4-6 mL Whole Blood
Container Type
Yellow (ACD), Solution A/B
Collection Instructions
Whole blood collected in an EDTA (lavender-top) tube is also acceptable.
Processing Information - Lab Use Only
Transport Temperature
Room Temp-OK/Refrigerate-OK
Specimen Stability
Room Temp: 6 Days; Refrigerated: 6 Days (preferred); Frozen: Unacceptable
Rejection Criteria
Gross hemolysis
Test Volume Required
6 mL Whole Blood
Minimum Test Volume
4 mL Whole Blood
Processing Instructions
Send whole blood specimen in original tube. Do not aliquot. Order in Mayolink and send with Mayo courier Monday-Friday.
Comments
For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerated within 6 days of collection to be stabilized. Pre-analytical processing is performed Monday through Friday and Sunday. This test may be canceled if specimens are outside of stability when processing occurs. Collect and package specimens for arrival on days when processing is performed.
CPT Codes
82657 (not genetic)
Revised
5/9/26
Initials
IM