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Lab Test Dictionary

Metanephrines, Fractionated, LC/MS/MS, Random Urine (14961X)


Kinetic Alkaline Picrate; Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)



Specimen Type

Urine, Random

Performing Lab

Quest Diagnostics San Juan Capistrano

Epic ID


Lab Test Days


Standard TAT

3-4 Days

Collection Information

Specimen Required

1.5-5 mL Random Urine

Container Type

Sterile Container

Collection Instructions

It is preferable for the patient to be off medication for three days prior to collection. Patient should avoid tobacco, tea, coffee for three days prior to specimen collection. Common antihypertensive (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blocker) casue minimal or no interference. Medications which are alpha agonists (Aldomet, alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room Temp: 7 Days (acidified); Refrigerated: 8 Days; Frozen: 30 Days

Test Volume Required

5 mL Random Urine

Minimum Test Volume

1.5 mL Random Urine

Processing Instructions

After urine collection, add 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is sent frozen.

Included Tests

Metanehrines, Normetanephrines, Total Metanephrines and Creatinine.

CPT Codes

82570, 83835