Jane Kim, M.D.

Bio

Dr. Jane Kim is a Clinical Professor of Pediatrics at the University of California, San Diego (UCSD) and a board-certified pediatric endocrinologist at Rady Children's Hospital San Diego (RCHSD). She is also the Fellowship Program Director for the UCSD Pediatric Endocrinology training program.

Her medical education began at the University of Toronto, followed by a pediatric residency at the Hospital for Sick Children. Committed to pursuing endocrine research that integrates molecular biology and clinical medicine, Dr. Kim moved to the National Institutes of Health headquarters in Bethesda, Md., where she completed her pediatric endocrinology fellowship. To gain additional expertise in diabetes research, she conducted postdoctoral research training at Columbia University, New York before coming to UCSD/Rady Children's Hospital.

Dr. Kim provides clinical care for children with all types of pediatric endocrine conditions. She also conducts research to better understand the causes and complications of diabetes, with the goal of discovering new treatments. She has published in several peer-reviewed journals on these topics. She is a faculty member in the UCSD Pediatric Diabetes Research Center and site investigator for clinical research related to both type 1 and type 2 diabetes.

Additionally, Dr. Kim instructs and mentors medical students, residents, and fellows at the UC San Diego School of Medicine.

When not working, Dr. Kim enjoys spending time with her family. She also enjoys music and was trained in classical music as a pianist.

Publications

The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids.
Mannochio-Russo H, Charron-Lamoureux V, van Faassen M, Lamichhane S, Gonçalves WD Nunes, Deleray V, Patan A, Vittali J, Rajkumar P, El Abiead Y, Zhao HN, Portal Gomes PW, Mohanty I, Lee C, Sund A, Sharma M, Liu Y, Pattynama D, Walker GT, Norton GJ, Khatib, Andalibi MS, Wang CX, Ellis RJ, Moore DJ, Iudicello JE, Franklin D Jr., Letendre S, Chin L, Walker C, Renwick S, Zemlin J, Meehan MJ, Song X, Kasper D, Burcham Z, Kim JJ, Kadakia S, Raffatellu M, Bode L, Zengler K, Wang M, Siegel D, Knight R, Dorrestein PC

The COVID-19 pandemic is associated with a substantial rise in frequency and severity of presentation of youth-onset type 2 diabetes.
Magge S, Wolf RM, Pyle L, Brown EA, Benavides VC, Bianco ME, Chao LC, Cymbaluk A, Gumus Balikcioglu P, Halpin K, Hsia DS, Huerta-Saenz L, Kim JJ, Kumar S, Levitt Katz LE, Marks BE, Neyman A, O’Sullivan KL, SabSasidharan Pillai S, Shah AS, Shoemaker AH, Siddiqui JAW, Srinivasan S, Inas H Thomas IH, Tryggestad JB, Yousif MF, Kelsey MM

Bayesian multivariate sparse functional principal components analysis with application to longitudinal microbiome multiomics data.
Jiang L, Elrod C, Kim JJ, Swafford AD, Knight R, Thompson WK

Incidence of New-Onset Type 1 Diabetes Among US Children During the COVID-19 Global Pandemic.
Gottesman BL, Yu J, Tanaka C, Longhurst CA, Kim JJ

Identification of Pathognomonic Purine Synthesis Biomarkers by Metabolomic Profiling of Youth with Type 2 Diabetes.
Concepcion JC, Chen K, Saito R, Mendez E, Gangoiti J, Barshop B, Natarajan L, Sharma K, Kim JJ

Distinct gene signatures predict insulin resistance in young mice with high fat diet-induced obesity.
Chen K, Jih A, Osborn O, Kavaler ST, Fu W, Sasik R, Saito R, Kim JJ

Age and High-Fat Diet Effects on Glutamine Synthetase Immunoreactivity in Liver and Hippocampus and Recognition Memory in Mice.
Soontornniyomkij V, Kesby JP, Soontornniyomkij B, Kim JJ, Kisseleva T, Achim CL, Semenova S, Jeste DV

Spatial cognition in adult and aged mice exposed to high-fat diet.
Kesby JP, Kim JJ, Scadeng M, Woods G, Kado D, Jeste DV, Achim CL, Semenova S

Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance.
Chen K, Jih A, Kavaler ST, Oh D, Lagakos WS, Kim JJ

The Fractalkine and CX3CR1 system regulates beta cell function and insulin secretion.
Lee YS, Morinaga H, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky JM

GPR105 ablation improves inflammation and insulin sensitivity in mice with diet-induced obesity.
Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Olefsky JM, Lazarowski E, Kim JJ

Deletion of G protein coupled receptor 21 (GPR21) improves insulin sensitivity in diet-induced obese mice.
Osborn O, Oh D, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM

Pancreatic beta-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency.
Kavaler S, Morinaga H, Jih A, Fan W, Hedlund M, Varki A, Kim JJ

FoxO1 regulates Tlr4 signaling and cell survival in macrophages.
Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM

FoxO1 haploinsufficiency protects against high fat diet-induced insulin resistance with enhanced PPARgamma activation in adipose tissue.
Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM

FOXO1 transrepresses PPARgamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes.
Fan W, Imamura T, Sonoda N, Sears DD, Patsouris D, Kim JJ, Olefsky JM

Analysis of compensatory β cell response in mice with combined mutations of the Insulin Receptor and Irs2.
Kim JJ, Kido Y, Scherer PE, White MA, Accili D

Mitogenic and metabolic effects of type I IGF receptor overexpression in insulin receptor-deficient hepatocytes.
Kim JJ, Park BC, Kido Y, Accili D