Methodology
Fluorescence In Situ Hybridization (FISH)
Specimen Type
Whole Blood or Bone Marrow
Performing Lab
Mayo Medical Laboratory
Epic ID
Other Reference Test
Lab Test Days
Monday-Friday
Standard TAT
7-10 Days
Collection Information
Specimen Required
2-6 mL Whole Blood or 1-3 mL Bone Marrow
Container Type
Yellow (ACD), Solution A/B
Collection Instructions
Whole blood or bone marrow collected in a Sodium Heparin (dark green-top) or an EDTA (lavender-top) tube is also acceptable.
Processing Information - Lab Use Only
Transport Temperature
Room Temp-OK/Refrigerate-OK
Specimen Stability
Room Temp: 6 Days (preferred); Refrigerated: 6 Days; Frozen: Unacceptable
Rejection Criteria
Fresh tissue
Test Volume Required
6 mL Whole Blood or 3 mL Bone Marrow
Minimum Test Volume
2 mL Whole Blood or 1 mL Bone Marrow
Processing Instructions
Send whole blood or bone marrow in original tube. Do not aliquot. Necessary Information: 1. A list of probes requested for analysis is required. Probes available for this test are listed in the Testing Algorithm section. 2. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories. 3. A flow cytometry and/or a bone marrow pathology report should be submitted with each specimen. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed. Order in MayoLink and send with Mayo courier Monday-Friday
Comments
Insurance authorization is required for Outpatients. Ok to send on Inpatients.
CPT Codes
88271 (x2), 88275, 88291
Revised
5/9/26
Initials
IM