Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms
PLP, P5P, Vitamin B6
Specimen Type
CSF
Performing Lab
Labcorp
Epic ID
Other Reference Test
Standard TAT
10-14 Days
Collection Information
Specimen Required
0.5 mL CSF
Container Type
Labcorp 5-Tube CSF Collection Kit (contact Lab)
Collection Instructions
Single-tube collection (if no additional testing is ordered): Collect the entire sample into a single sterile tube from a standard LP.***CSF collection protocol: Collect CSF starting from the first drop directly into the first tube. Do not aliquot from a pooled sample. Fill tubes in numerical order, to the volume listed below: Tube 1: 0.5 mL, Tube 2: 1.0 mL, Tube 3: 1.0 mL (contains antioxidants to preserve sample integrity), Tube 4: 1.0 mL, Tube 5: 1.0 mL***If no blood contamination, place tubes on dry ice immediately at bedside (contact lab for dry ice). If blood contamination is present, send to lab ASAP so sample can be centrifuged immediately
Processing Information - Lab Use Only
Transport Temperature
Frozen-Only
Specimen Stability
14 Days
Rejection Criteria
Thawed
Test Volume Required
0.5 mL CSF
Minimum Test Volume
0.25 mL CSF
Processing Instructions
If blood contamination is present, centrifuge immediately (before freezing). Transfer clear CSF to new, correspondingly labeled tube, then place the tube on dry ice immediately. Label tubes with patient information leaving the tube number viewable. If no blood contamination freeze immediately. Fill out Labcorp requisition and send with daily courier pick up.
Revised
10/19/26
Initials
IM