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Lab Test Dictionary

Dihydropyrimidine Dehydrogenase (DPYD) (2012166)

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring


Synonyms

Fegafur, 5FU drug toxicity, DPYD genotyping, Xeloda, DPD, Capecitabine, Uftoral

Specimen Type

Blood

Performing Lab

ARUP


Epic ID

Other Reference Test

Lab Test Days

Varies

Standard TAT

5 to 10 days


Collection Information

Specimen Required

3 mL blood

Container Type

Lavender EDTA tube

Collection Instructions

Also acceptable Pink (K2EDTA) or Yellow (ACD Solution A or B tube


Processing Information - Lab Use Only

Transport Temperature

Refrigerated

Specimen Stability

Room Temp=72 hours, Refrigerated=1 week

Test Volume Required

3 mL blood

Minimum Test Volume

1 mL blood


Comments

Predicts risk of dose-related toxicity to 5-FU therapy. Requires insurance auth.


CPT Codes

81232 (genetic)


Revised

7/29/25