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Lab Test Dictionary

TCR V-Beta Repertoire Analysis by Spectratyping, Blood (TCRB)


Molecular TCR Vb-CDR3 Fragment Length Analysis


Bone marrow transplantation; DiGeorge Syndrome; Hematopoietic cell transplantation; Immune Reconstitution; Immune System Diversity; Immunological Recovery; Leaky SCID; Oligoclonal T Cell; Omenn Syndrome; Primary Immunodeficiency; SCID; Spectratyping; T cell diversity; T cell recovery; T Cell Repertoire; T cell spectratype; TCR V-beta, TCR V-beta, TCRVB

Specimen Type

Whole Blood

Performing Lab

Mayo Medical Lab

Epic ID

Other Reference Test

Lab Test Days


Standard TAT

10-14 Days

Collection Information

Specimen Required

Adults: 5-10 mL Whole Blood; Pediatrics: 1-3 mL Whole Blood

Container Type

Lavender (EDTA)

Collection Instructions

Collect Monday-Thursday only, no weekends or holidays. Physician must complete the Mayo TCR V beta Spectratyping Assay Patient Info (T719) form and submit with specimen to the lab.

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room Temp: 48 Hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Rejection Criteria

Gross hemolysis; Clotted

Test Volume Required

Adults: 10 mL Whole Blood; Pediatrics: 3 mL Whole Blood

Minimum Test Volume

Adults: 5 mL Whole Blood; Pediatrics: 1 mL Whole Blood

Processing Instructions

Submit the completed Mayo TCR V beta Spectratyping Assay Patient Info (T719) form with specimen room temp same day as collected Monday-Thursday only, no weekends or holidays.


Insurance authorization is required prior to draw for Outpatients. MJ approval is required for Inpatients.

CPT Codes