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Lab Test Dictionary

Thrombosis Panel (11051)


Clotting Assay; Clot Detection; Chromogenic Substrate; RVVT-based Assay (Clot-based)


Protein C Activity; Protein S Activity; Antithrombin III Activity (AT3); Activated Protein C-Resistance

Specimen Type


Performing Lab

Quest Diagnostics San Juan Capistrano

Epic ID


Collection Information

Specimen Required

(three-six) 1.8 mL or (two-four) 2.7 mL Blood

Container Type

Light Blue (Sodium Citrate)

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room Temp: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 Months

Test Volume Required

5 mL Platelet-Poor Plasma

Minimum Test Volume

2.5 mL Platelet-Poor Plasma

Processing Instructions

Platelet poor plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and send frozen.

Included Tests

Protein C Activity, Protein S Activity, Antithrombin III Activity (AT3) and Activated Protein C Resistance.

CPT Codes

85300, 85303, 85306, 85307