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Lab Test Dictionary

Thyroid Cancer Mutation Panel (BRAF, RAS, RET/PTC, PAX8/PPAR) (90469)

Specimen Type

See Below

Performing Lab

Quest Diagnostics San Juan Capistrano

Epic ID

Other Reference Test

Lab Test Days


Standard TAT

5-6 Days

Collection Information

Specimen Required

Needle washings, 2-4 slides or formalin-fixed paraffin embedded tissue

Container Type

Paraffin Embedded Tissue Block

Collection Instructions

Needle washings in alcohol based fixative (e.g. cytolyt), 2-4 slides, or formalin-fixed, paraffin embedded tissue block. FNA or FFPE specimens are acceptable for the assay. All specimens must be accompanied with pathology report. Specimens will be examined by a pathologist for confirmation and microdissection if warranted. A minimum of 4 FNA slides should be submitted and three should be without coverslips. Coverslipped slides will delay reporting of results.

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room tempe: Indefinite; Refrigerated: Indefinite; Frozen: Unacceptable

Rejection Criteria

Baked slides; Received frozen

Test Volume Required

4 Slides Tissue or 4 Slides FNA

Minimum Test Volume

2 Slides Tissue or 4 Slides FNA

Processing Instructions

All specimens must be accompanied with pathology report.

Included Tests

BRAF Mutation Analysis, Papillary Thyroid Cancer; RAS Mutation Analysis, Thyroid Cancer; RET/PTC Rearrangement, Thyroid Cancer; PAX8/PPAR[gamma] Translocation and Thyroid Cancer


Insurance authorization required prior to draw for outpatients. Ok to send on inpatients.

CPT Codes

81210, 81403, 81275, 81276, 81311, 81479, 81401