A. Preethi Ganesan, M.D., Ph.D.

Locations

3020 Children's Way
MC 5035
San Diego, CA 92123

Specialty

Hematology/Oncology

Organization

Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Medical School

Madras Medical College

Residency

Royal College of Pediatrics + Child Health, London

Fellowship

Rady Childrens Hospital-San Diego

Bio

Dr. Preethi Ganesan is a hematologist/oncologist at Rady Children's Hospital-San Diego. She provides inpatient care to patients with leukemia and lymphoma, which are her clinical interests.

Her research is focused on studying the dynamic interaction between the tumor immune-microenvironment and cancer stem cells that drive relapse. She seeks to investigate immune responses in pediatric tumors, with the ultimate goal of finding a novel immunotherapy.

During her fellowship at Rady Children's and UC San Diego, Dr. Ganesan evaluated the molecular profile of tumor-infiltrating lymphocytes isolated from patients with cancer and discovered that a distinct subset of T cells predict improved patient survival (in press, Nature Immunology). In her doctoral work, using patient tumor samples and a transgenic mouse model of cancer, she demonstrated the role of T regulatory cells in propelling tumor growth and mechanistically demonstrated that this was mediated by inhibition of anti-tumor CD8 cytotoxic T lymphocyte recruitment and function within tumors.

Dr. Ganesan completed her pediatric residency and doctoral program in tumor immunology, both in the United Kingdom. Among her honors and accomplishments, she received the Ray Owen Award for Outstanding Postdoctoral Scholar in 2017, a Hyundai Hope on Wheels Research Scholar grant in 2016 and a Berkeley Fellowship, awarded by University College London and Gonville & Caius College Cambridge, in 2013.

Publications

Obstructive sleep apnoea as a presenting manifestation of non-Hodgkin lymphoma in a child.
Ganesan AP, Jiang W, Kuo DJ, Bhattacharjee R

Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer.
Ganesan AP, Clarke J, Wood O, Garrido-Martin EM, Chee SJ, Mellows T, Samaniego-Castruita D, Singh D, Seumois G, Alzetani A, Woo E, Friedmann PS, King EV, Thomas GJ, Sanchez-Elsner T, Vijayanand P, Ottensmeier CH

Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma.
Ganesan AP, Johansson M, Ruffell B, Yagui-Beltrán A, Lau J, Jablons DM, Coussens LM

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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