, Gastroenterology, Hepatology and Nutrition


Gastroenterology, Hepatology and Nutrition


Rady Children's Specialists of San Diego

Medical Group / IPA


Medical School

University of Arkansas for Medical Sciences


University of Arkansas for Medical Sciences


University of Arkansas for Medical Sciences


Stanford University School of Medicine

Board Certifications

Gastroenterology, Hepatology and Nutrition, Pediatrics





Probiotics and Probiotic-Derived Functional Factors-Mechanistic Insights Into Applications for Intestinal Homeostasis
Yan F and Polk DB

Production of a Functional Factor, p40, by Lactobacillus rhamnosus GG Is Promoted by Intestinal Epithelial Cell-Secreted Extracellular Vesicles
Yang L, Higginbotham J, Liu L, Zhao G, Weaver A, Peek RM, Polk DB, Li H, Yan F

Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes
Shen x, Liu L, Peek RM, Acra SA, Moore DJ, Wilson KT, He F, Polk DB, Yan F

Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice
Dube PE, Liu CY, Girish N, Washington MK and Polk DB

Epidermal growth factor suppresses intestinal epithelial cell shedding through a MAPK-dependent pathway
Miguel JC, Maxwell AA, Hsieh JJ, Harnisch LC, Al Alam D, Polk DB, Lien CL, Watson AJ, and Frey MR

Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood
Yan F, Liu L, Cao H, Moore DJ, Washington MK, Wang B, Peek RM, Acra SA, and Polk DB

An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells
Wang Y, Liu L, Moore, DJ, Shen, X, Peek, RM, Acra, SA, Li, H, Ren, X, Polk, DB, and Yan, F

Activation of Epidermal Growth Factor Receptor in Macrophages Mediates Feedback Inhibition of M2 Polarization and Gastrointestinal Tumor Cell Growth
Zaho G, Liu L, Peek RM Jr, Hao X, Polk DB, Li H, and Yan F

Preserving viability of Lactobacillus rhamnosus GG in vitro and in vivo by a new encapsulation system
Li R, Zhang Y, Polk DB, Tomasula PM, Yan F, and Liu L

Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8(+) T Cells in Mice With Colitis
Punit S, Dub? PE, Liu CY, Girish N, Washington MK, and Polk DB

Optical reconstruction of murine colorectal mucosa at cellular resolution
Liu CY, Dub? PE, Girish N, Reddy AT, and Polk DB

Predicting persistence of functional abdominal pain from childhood into young adulthood
Horst S, Shelby G, Anderson J, Acra S, Polk DB, Saville BR, Garber J, and Walker, LS

Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis
Ahmad R, Chaturvedi R, Olivares-Villag?mez D, Habib T, Asim M, Shivesh P, Polk DB, Wilson KT, Washington MK, Van Kaer L, Dhawan P, and Singh AB

Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage
Chaturvedi, R, Asim M, Piazuelo MB, Yan F, Barry DP, Sierra JC, Delgado, AG, Hill S, Casero RA Jr, Bravo LE, Dominguez RL, Correa P, Polk DB

Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis
Lu N, Wang L, Cao H, Liu L, Van Kaer L, Washington MK, Rosen MJ, Dube PE, Wilson KT, Ren X, Hao X, Polk DB, and Yan F

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