3020 Children's Way
San Diego, CA 92123
Rady Children's Specialists of San Diego
University of Texas
UC San Diego
UC San Diego
UC San Diego
Pediatric Cardiology, Pediatrics
Dr. Paul Grossfeld is a board-certified pediatric cardiologist at Rady Children's Hospital-San Diego and an associate clinical professor at UC San Diego School of Medicine. He treats both pediatric and adult patients with congenital heart disease.
After earning his medical degree at the University of Texas Southwestern School of Medicine in 1992, he went on to complete his pediatrics residency training in 1995 at UC San Diego, followed by a pediatric cardiology fellowship at UC San Diego in 1999.
Dr. Grossfeld has a particular interest in treating patients with rare genetic syndromes and serves as the chief medical advisor for the 11q Research and Resource Group. He also directs a basic science research laboratory at UC San Diego dedicated to studying genetic causes of congenital heart disease.
Along with his clinical and research responsibilities, Dr. Grossfeld directs the pediatric cardiology fellowship program and is actively engaged in teaching fellows, residents and medical students.
Among his professional activities, he and his wife, Susan, lead an annual cardiac surgical mission to the Angkor Hospital for Children in Siem Reap, Cambodia. Dr. Grossfeld also serves as a cardiology consultant for the United States men's and women's volleyball teams.
When not working, Dr. Grossfeld enjoys spending time with his wife and son, Stefan, traveling, and playing sports, including competitive tennis, golf and swimming in La Jolla cove.
Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease?
Grossfeld P, Nie S, Lin L, Wang L, Anderson RH
Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
Xu L, Fu M, Chen D, Han W, Ostrowski MC, Grossfeld P, Gao P, Ye M
Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P
Arterial Switch Operation in a Patient With Ehlers-Danlos Syndrome Type IV.
Murthy R, Herrick NL, El-Said H, Grossfeld P, Moore J, Lamberti JJ
Evidence That Deletion of ETS-1, a Gene in the Jacobsen Syndrome (11q-) Cardiac Critical Region, Causes Congenital Heart Defects through Impaired Cardiac Neural Crest Cell Function
Ye M, Yin Y, Fukatsu K, Grossfeld P, Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H
Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.
van Vliet PP, Lin L, Boogerd CJ, Martin JF, Andelfinger G, Grossfeld PD, Evans SM
The complex genetics of hypoplastic left heart syndrome.
Liu X, Yagi H, Saeed S, Bais AS, Gabriel GC, Chen Z, Peterson KA, Li Y, Schwartz MC, Reynolds WT, Saydmohammed M, Gibbs B, Wu Y, Devine W, Chatterjee B, Klena NT, Kostka D, de Mesy Bentley KL, Ganapathiraju MK, Dexheimer P, Leatherbury L, Khalifa O, Bhagat A, Zahid M, Pu W, Watkins S, Grossfeld P, Murray SA, Porter GA Jr, Tsang M, Martin LJ, Benson DW, Aronow BJ, Lo CW
Utility of Genetic Testing in Elite Volleyball Players with Aortic Root Dilation.
Herrick N, Davis C, Vargas L, Dietz H, Grossfeld P
PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking.
Nakamura T, Arima-Yoshida F, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akshoomoff N, Mattson SN, Grossfeld PD, Manabe T, Akiyama T
Transcriptional Impact of Rare and Private Copy Number Variants in Hypoplastic Left Heart Syndrome.
Glidewell SC, Miyamoto SD, Grossfeld PD, Clouthier DE, Coldren CD, Stearman RS, Geraci MW
Jacobsen syndrome: Advances in our knowledge of phenotype and genotype.
Favier R, Akshoomoff N, Mattson S, Grossfeld P
Cardiovascular and Musculoskeletal Assessment of Elite US Volleyball Players.
Davis CK, Dyar DA, Vargas LA, Grossfeld PD
Atenolol versus losartan in children and young adults with Marfan's syndrome.
Lacro RV, Dietz HC, Sleeper LA, Yetman AT, Bradley TJ, Colan SD, Pearson GD, Selamet Tierney ES, Levine JC, Atz AM, Benson DW, Braverman AC, Chen S, De Backer J, Gelb BD, Grossfeld PD, Klein GL, Lai WW, Liou A, Loeys BL, Markham LW, Olson AK, Paridon SM, Pemberton VL, Pierpont ME, Pyeritz RE, Radojewski E, Roman MJ, Sharkey AM, Stylianou MP, Wechsler SB, Young LT, Mahony L, Pediatric Heart Network Investigators.
Evidence for autism spectrum disorder in Jacobsen syndrome: identification of a candidate gene in distal 11q.
Akshoomoff N, Mattson SN, Grossfeld PD
Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.
Ye M, Parente F, Li X, Perryman MB, Zelante L, Wynshaw-Boris A, Chen J, Grossfeld P
Somatic mutations in NKX2â€“5, GATA4, and HAND1 are not a common cause of tetralogy of Fallot or hypoplastic left heart.
Esposito G, Butler TL, Blue GM, Cole AD, Sholler GF, Kirk EP, Grossfeld P, Perryman BM, Harvey RP, Winlaw DS
Clinical, pathological, and molecular analyses of cardiovascular abnormalities in Costello syndrome: a Ras/MAPK pathway syndrome.
Lin AE, Alexander ME, Colan SD, Kerr B, Rauen KA, Noonan J, Baffa J, Hopkins E, Sol-Church K, Limongelli G, Digilio MC, Marino B, Innes AM, Aoki Y, Silberbach M, Delrue MA, White SM, Hamilton RM, O'Connor W, Grossfeld PD, Smoot LB, Padera RF, Gripp KW
Cognitive-behavioral features of Wolf-Hirschhorn syndrome and other subtelomeric microdeletions.
Fisch GS, Grossfeld P, Falk R, Battaglia A, Youngblom J, Simensen R
Successful surgical closure of an arterial duct in 18 children in a third world country.
Grossfeld P, Greenberg M, Saw S, Cheng G, Stanzi A, Mathewson J, Pises N, Lyda L, Vuthy S, Elias W, Moriarty S, Levy S, Walter D, Panzarella P, Grossfeld S, Kriett J, Madani M
Fulminant myocarditis associated with pandemic H1N1 influenza A virus in children.
BratincsÃ¡k A, El-Said HG, Bradley JS, Shayan K, Grossfeld PD, Cannavino CR
Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.
Ye M, Coldren C, Liang X, Mattina T, Goldmuntz E, Benson DW, Ivy D, Perryman MB, Garrett-Sinha LA, Grossfeld P
Deletion of JAM-C, a candidate gene for heart defects in Jacobsen syndrome, results in a normal cardiac phenotype in mice.
Ye M, Hamzeh R, Geddis A, Varki N, Perryman MB, Grossfeld P
Hypoplastic left heart syndrome: new genetic insights.
Grossfeld P, Ye M, Harvey R
Myocardial inflammation, cellular death, and viral detection in sudden infant death caused by SIDS, suffocation, or myocarditis.
Krous HF, Ferandos C, Masoumi H, Arnold J, Haas EA, Stanley C, Grossfeld PD
See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.
PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.
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