Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Other Reference Test
2 mL blood
Red Top with Gel Barrier
After separation from cells: Room Temp=48 hours, Refrigerated=2 weeks, Frozen=1 year
Other body fluids. Contaminated, hemolyzed, grossly icteric or severely lipemic specimens.
0.5 mL serum
0.15 mL serum
Centrifuge & separate serum
IgG antibodies to HMGCR are mainly associated with necrotizing autoimmune myopathy (NAM) in a subset of statin-treated patients. Although infrequest, these antibodies may also be observd in statin-naive patients with NAM. Strong clinical correlation is recommended in the absence of muscle fiber necrosis, elevated serum creatinine kinase, perimysial pathology, and/or statin exposure.