Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Synonyms
3MT; 3-methoxy-4-hydroxyphenethylamine; Methoxytyramine; Methoxytramine; 3-Methoxytramine; 3-Methoxytyramine; Urine Dopamine
Specimen Type
Urine, Timed Collection
Performing Lab
Mayo Medical Lab
Epic ID
Other Reference Test
Lab Test Days
Monday-Friday; 4 P.M.
Standard TAT
3-5 Days
Collection Information
Specimen Required
2-10 mL 24-Hour Urine
Container Type
Sterile Container
Collection Instructions
Patient Preparation: Tricyclic antidepressants, labetalol, and sotalol medications may elevate levels of catecholamines producing results that cannot be interpreted. If clinically feasible, it is optimal to discontinue these medications at least 1 week before collection. Levodopa (Sinemet) medication will cause false-positive results. For advice on assessing the risk of removing patients from these medications and alternatives, you may consider consultation with a specialist in endocrinology or hypertension. Complete 24-hour urine collections are preferred, especially for patients with episodic hypertension; ideally the collection should begin at the onset of a "spell." Add 10 g (pediatric: 3 g) of boric acid as preservative within 4 hours of completion of the collection.
Processing Information - Lab Use Only
Transport Temperature
Refrigerate-OK/Frozen-OK/Ambient-OK
Specimen Stability
Room Temp: 28 Days; Refrigerated: 28 Days (Preferred); Frozen: 90 Days
Test Volume Required
10 mL 24-Hour Urine
Minimum Test Volume
2 mL 24-Hour Urine
Processing Instructions
Add 10 g (pediatric: 3 g) of boric acid or 50% Acetic Acid as preservative (preferred) within 4 hours of completion of the collection. 6M Hydrochloric Acid, 6M Nitric Acid, Sodium Carbonate or Toluene as preservatives are also acceptable. 24-Hour volume is required. Order in Mayolink and send with Mayo courier Monday-Friday.
CPT Codes
82542
Revised
09-11-19
Initials
SL