Lab Test Dictionary

Alpha Beta Double-Negative T Cells for Autoimmune Lymphoproliferative Syndrome, Blood (ALPS)

Methodology

Flow Cytometry

Synonyms

Canale-Smith syndrome; CD4/CD8 negative; DNT (Double Negative T-Cells); Double negative T cells (DNT); Alpha/Beta positive

Specimen Type

Whole Blood

Performing Lab

Mayo Medical Lab

Epic ID

LAB08992

Lab Test Days

Monday-Friday

Standard TAT

3-4 Days

Collection Information

Specimen Required

0.5-3 mL Whole Blood

Container Type

Lavender (EDTA)

Collection Instructions

Collect Monday-Thursday 0800-1300 ONLY, no Fridays, weekends or holidays. Collect and package specimen as close to shipping time as possible. It is recommended that specimens arrive within 24 hours of collection. Samples arriving on the weekend and observed holidays may be canceled.

Processing Information - Lab Use Only

Transport Temperature

Ambient-Only

Specimen Stability

Room Temp: 72 Hours (recieved over 24 hours will require a disclaimer); Refrigerated: Unacceptable; Frozen: Unacceptable

Rejection Criteria

Gross hemolysis; Gross lipemia

Test Volume Required

3 mL Whole Blood

Minimum Test Volume

0.5 mL Whole Blood

Processing Instructions

Order in Mayolink and send with Mayo courier Monday-Thursday, no Fridays, weekends or holidays. Testing performed Monday-Friday. Collect and package specimen as close to shipping time as possible. It is recommended that specimens arrive within 24 hours of collection. Samples arriving on the weekend and observed holidays may be canceled.

Comments

No insurance authorization required.

CPT Codes

86356 (x2), 86359

Revised

9/10/25