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Lab Test Dictionary

Anemia Profile, Megaloblastic


Vitamin B12; Cobalamin Deficiency

Specimen Type

Serum or Plasma

Performing Lab

Quest forwards to LabCorp (TSO)

Epic ID

Other Reference Test

Lab Test Days

Monday, Wednesday, Friday

Standard TAT

4 Days

Collection Information

Specimen Required

2-4 mL Blood

Container Type

Red Top (No Additive)

Collection Instructions

Plasma collected in a heparin (green-top) tube is also acceptable.

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room Temp: 14 Days; Refrigerated: 14 Days; Frozen: 14 Days

Test Volume Required

2 mL Serum or Plasma

Minimum Test Volume

1 mL Serum or Plasma

Processing Instructions

Centrifuge and separate within one hour of collection. TSO required.

Included Tests

Cystathionine, Homocysteine, 2-Methylcitric acid and Methylmalonic acid


Useful for diagnosing and distinguishing between B12 and folate deficiency. Elevated levels of methylmalonic acid provide an early indication of cobalamin (B12) deficiency. LabCorp test code: 706960. Requires TSO form.

CPT Codes

82136, 83918