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Lab Test Dictionary

BCR/ABL1, p210, mRNA Detection, RT-PCR, Quantitative, Monitoring CML (BCRAB)

Methodology

Quatitative Reverse Transcription-Polymerase Chain Reaction (RT-PCR) using GeneXpert (Cepheid)


Synonyms

Chronic Myelogenous Leukemia (CML); CML RT-PCR; Philadelphia Chromosome Ph1 Bone Marrow/Blood; BCR/ABL

Specimen Type

Whole Blood or Bone Marrow

Performing Lab

Mayo Medical Lab


Epic ID

LAB00116

Lab Test Days

Monday-Friday

Standard TAT

5-6 Days


Collection Information

Specimen Required

1-4 mL Whole Blood or 1-3 mL Bone Marrow

Container Type

Lavender (EDTA)

Collection Instructions

Whole blood or bone marrow collected in an ACD (yellow-top) tube is also acceptable. Collect Monday-Thursday before 1300 ONLY, no weekend or holidays. Pertinent clinical history including if the patient has a diagnosis of chronic myelogenous leukemia or other bcrlabl-positive neoplasma. Physician must complete the Mayo Hematopathology Patient Info form and submit with specimen to lab.


Processing Information - Lab Use Only

Transport Temperature

Refrigerate-OK/Ambient-OK

Specimen Stability

Room Temp: 72 Hours; Refrigerated: 72 Hours; Frozen: Unacceptable

Rejection Criteria

Gross hemolysis

Test Volume Required

4 mL Whole Blood or 3 mL Bone Marrow

Minimum Test Volume

1-4 mL Whole Blood or Bone Marrow

Processing Instructions

Indicate source in comments and on specimen. Pertinent clinical history including if the patient has a diagnosis of chronic myelogenous leukemia or other bcrlabl-positive neoplasma. Submit completed Mayo Hematopathology Patient Info form with specimen room temp.


Comments

Insurance authorization required prior to draw for outpatients. Ok to send on inpatients.


CPT Codes

81206


Revised

02-13-17

Initials

SL