Methodology
Polymerase Chain Reaction (PCR), Fluorescence Monitoring
Synonyms
2C19; Cytochrome P450 2C19 Genotype
Specimen Type
Whole Blood
Performing Lab
ARUP
Epic ID
Other Genetic Test
Lab Test Days
Varies
Standard TAT
5-10 Days
Collection Information
Specimen Required
1-3 mL Whole Blood
Container Type
EDTA (Lavender-Top) Tube
Processing Information - Lab Use Only
Transport Temperature
Refrigerated-OK/Frozen-OK
Specimen Stability
Room Temp: 72 Hours; Refrigerated: 1 Week (preferred); Frozen: 1 Month
Rejection Criteria
Plasma or serum; Specimens collected in sodium heparin or lithium heparin
Test Volume Required
3 mL Whole Blood
Minimum Test Volume
1 mL Whole Blood
Processing Instructions
Complete an ARUP requisition and submit with specimen refrigerated and specimen with courier Monday-Friday.
Included Tests
CYP2C19 Phenotype and CYP2C19 Genotype.
Comments
Assesses genetic risk of abnormal drug metabolism for CYP2C19 substrates. May aid in drug selection and dose planning for drugs metabolized by CYP2C19. Insurance authorization is required prior to draw for Outpatients. Ok to send on Inpatients.
CPT Codes
81225
Revised
9/12/25
Initials
SA