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Lab Test Dictionary

Metanephrines, Fractionated, LC/MS/MS, 24-Hour Urine (14962X)


Liquid Chromatography, Tandem Mass Spectrometry (LC/MS/MS)

Specimen Type

Urine, Timed Collection

Performing Lab

Quest Diagnostics San Juan Capistrano

Epic ID


Lab Test Days


Standard TAT

3-4 Days

Collection Information

Specimen Required

1.5-5 mL 24-Hour Urine

Container Type

24-Hour Urine Container

Collection Instructions

It is preferred for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitiors, calcium channel blockers, alpha nad beta blockers) cause minimal or no interferance. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

Processing Information - Lab Use Only

Transport Temperature


Specimen Stability

Room Temp: 7 Days; Refrigerated: 8 Days; Frozen: 30 Days

Test Volume Required

5 mL 24-Hour Urine

Minimum Test Volume

1.5 mL 24-Hour Urine

Processing Instructions

After urine collection, add 25 mL of 6N HCl to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and the sample is shipped frozen. Indicate total volume and pH in comments, on specimen and on batch sheet.

Included Tests

Metanephrine, Normetanephrine and Total Metanephrines.

CPT Codes