Methodology
Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
Synonyms
TPMT Enzyme Activity, 6-TGN (6-thioguanine) and 6-MMPN (6-methylmercaptopurine),Thiopurine S-methyltransferase
Specimen Type
Whole Blood
Performing Lab
Quest Diagnostics San Juan Capistrano
Epic ID
LAB001718
Lab Test Days
Sunday-Thursday
Standard TAT
4-6 Days
Collection Information
Specimen Required
2-4 mL (x2) Whole Blood
Container Type
Lavender (EDTA)
Collection Instructions
Collect venous blood in 2 separate EDTA (lavender-top) tubes (2-4mL in each tube). Blood is collected prior to azathioprine (imuran) or 6-mercaptopurine (6mp, purinethol) therapy for screening purposes.
Processing Information - Lab Use Only
Transport Temperature
Refrigerate-Only
Specimen Stability
Room Temp: 48 Hours; Refrigerated: 9 Days; Frozen: Unacceptable
Rejection Criteria
Hemolysis; Clotted; Animal specimen; Forensic specimen
Test Volume Required
4 mL (x2) Whole Blood
Minimum Test Volume
2 mL (x2) Whole Blood
Processing Instructions
Quest will accept 3 mL (x1) Whole Blood in EDTA (lavender-top) tube, if collected.
CPT Codes
80375
Revised
12-17-17
Initials
SL