Robert Mak, M.D., Ph.D.


3020 Children's Way
MC 5137
San Diego, CA 92123




Rady Children's Specialists of San Diego

Medical Group / IPA

Rady Children's Specialists

Medical School

University of Hong Kong, University of London


Guy's Hospital Medical School, Queen Elizabeth Hospital of Hong Kong


Guys and St Thomas Hospital NHS Trust, Karlsruhe Hospital, Yale University School of Medicine




Dr. Robert Mak is chief of the Pediatric Nephrology Division at Rady Children's Hospital-San Diego and a tenured professor of pediatrics at UC San Diego.

He completed a pediatric residency and pediatric nephrology fellowship at Guy's Hospital Medical School. He also received his PhD in pediatric nephrology at University of London before enrolling in postdoctoral research training at Yale University and Heidelberg University. He was a faculty member at Stanford University, University of Southern California and Oregon Health and Science University before joining UC San Diego.

Dr. Mak has served as council representing the United States and chair of the global education committee for the International Pediatric Nephrology Association. He participated in several study sections at the National Institute of Health. He co-founded and served as president of the Western Society of Pediatric Nephrology. He is also on the editorial board for several medical journals, including Nature Reviews Nephrology, World Journal of Pediatrics, World Journal of Nephrology and World Journal of Hypertension.

His research interests include energy homeostasis, bone-mineral and cardiovascular complications as well as mechanisms of progression in chronic kidney disease. His laboratory is studying the molecular mechanism of cachexia associated with chronic kidney disease using rodent models. He has served on and chaired committees for a wide variety of research projects and clinical trials. He has also trained many postdoctoral fellows who in the past three years have won several regional and national scientific research awards from societies such as the Western Society of Pediatric Nephrology, American Society of Pediatric Nephrology and the Pediatric Academic Societies of the United States.


Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis.
Cheung WW, Cherqui S, Ding W, Esparza M, Zhou P, Shao J, Lieber RL, Mak RH

Cachexia in children with chronic kidney disease: challenges in diagnosis and treatment.
Mak RH

Inflammation and nutrition in children with chronic kidney disease.
Tu J, Cheung WW, Mak RH

Evaluation and management of hydronephrosis in the neonate.
Oliveira EA, Oliveira MC, Mak RH

Nephrology research--the past, present and future.
Floege J, Mak RH, Molitoris BA, Remuzzi G, Ronco P

Transplantation: Outcomes of prenatal immunosuppression.
Mak RH, Hoffman HM

Impact of obesity on kidney function and blood pressure in children.
Ding W, Cheung WW, Mak RH

Predictors of Rapid Progression of Glomerular and Nonglomerular Kidney Disease in Children and Adolescents: The Chronic Kidney Disease in Children (CKiD) Cohort.
Warady BA, Abraham AG, Schwartz GJ, Wong CS, Muñoz A, Betoko A, Mitsnefes M, Kaskel F, Greenbaum LA, Mak RH, Flynn J, Moxey-Mims MM, Furth S

Nephrotic syndrome: Efficacy of rituximab in challenging nephrotic syndrome.
Lemley KV, Mak RH

Early markers of obesity-related renal injury in childhood.
Ding W, Mak RH

Exploiting the therapeutic potential of leptin signaling in cachexia.
Mak RH, Cheung WW, Gertler A

Chronic kidney disease: Prenatal risk factors for kidney and urinary tract anomalies.
Mak RH, Schaefer F

C/EBPα regulates macrophage activation and systemic metabolism.
Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J

Growth in children with chronic kidney disease: role of nutrition, growth hormone, dialysis, and steroids.
Ingulli EG, Mak RH

Protein energy wasting in children with chronic kidney disease.
Abraham AG, Mak RH, Mitsnefes M, White C, Moxey-Mims M, Warady B, Furth SL

A pegylated leptin antagonist ameliorates CKD-associated cachexia in mice.
Cheung WW, Ding W, Gunta SS, Gu Y, Tabakman R, Klapper LN, Gertler A, Mak RH

Nephrotic syndrome: Genetic screening in steroid-resistant nephrotic syndrome.
Mak RH, Smoyer WE

The effect of vitamin D status on risk factors for cardiovascular disease.
Gunta SS, Thadhani RI, Mak RH

Ghrelin and leptin pathophysiology in chronic kidney disease.
Gunta SS, Mak RH

Dialysis: Vascular access in children--arteriovenous fistula or CVC?
Mak RH, Warady BA

Is obesity a risk factor for chronic kidney disease in children?
Gunta SS, Mak RH

Nephrotic syndrome in an 18-year-old boy with congenital myelomeningocele: questions.
Carter CE, Shayan K, Mak RH, Yorgin PD, Krous HF

Melanocortin antagonism ameliorates muscle wasting and inflammation in chronic kidney disease.
Cheung WW, Mak RH

MicroRNAs: a new therapeutic frontier for muscle wasting in chronic kidney disease.
Mak RH, Cheung WW

Erratum to: Wasting in chronic kidney disease.
Mak RH, Ikizler TA, Kovesdy CP, Raj DS, Stenvinkel P, Kalantar-Zadeh K

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.