Jane Burns, M.D.

Bio

Dr. Jane C. Burns is the director of the Kawasaki Disease Clinic at Rady Children's Hospital-San Diego and the Kawasaki Disease Research Center at UC San Diego. She is also a professor of pediatrics at UC San Diego School of Medicine.

After earning her medical degree at the University of North Carolina in Chapel Hill in 1978, she completed her pediatric residency and fellowship at the University of Colorado in Denver, followed by additional training in pediatric infectious diseases and molecular virology at Harvard Medical School and Boston Children's Hospital. She joined the faculty at Harvard Medical School in 1986 and moved to San Diego in 1990.

Internationally known for her research on Kawasaki disease (KD), her passion for studying KD has spanned almost three decades, with her first publication in 1982. In addition to her academic pursuits, Dr. Burns is the mother of two daughters. Her husband, John B. Gordon M.D., is an interventional cardiologist who cares for adults with long-term sequelae of KD. Together, working with a team from UC San Diego, they launched the Adult KD Collaborative, a long-range epidemiologic and clinical study of cardiovascular biomarkers and functional studies in adults who suffered from KD in childhood.

Publications

Infliximab for intensification of primary therapy for patients with Kawasaki disease and coronary artery aneurysms at diagnosis.
Miyata K, Bainto EV, Sun X, Jain S, Dummer KB, Burns JC, Tremoulet AH

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.
Habgood-Coote D, Wilson C, Shimizu C, Barendregt AM, Philipsen R, Galassini R, Calle IR, Workman L, Agyeman PKA, Ferwerda G, Anderson ST, van den Berg JM, Emonts M, Carrol ED, Fink CG, de Groot R, Hibberd ML, Kanegaye J, Nicol MP, Paulus S, Pollard AJ, Salas A, Secka F, Schlapbach LJ, Tremoulet AH, Walther M, Zenz W, Pediatric Emergency Medicine Kawasaki Disease Research Group (PEMKDRG), UK Kawasaki Genetics consortium, GENDRES consortium, EUCLIDS consortium, PERFORM consortium, Van der Flier M, Zar HJ, Kuijpers T, Burns JC, Martinón-Torres F, Wright VJ, Coin LJM, Cunnington AJ, Herberg JA, Levin M, Kaforou M

Subgroups of children with Kawasaki disease: a data-driven cluster analysis.
Wang H, Shimizu C, Bainto E, Hamilton S, Jackson HR, Estrada-Rivadeneyra D, Kaforou M, Levin M, Pancheri JM, Dummer KB, Tremoulet AH, Burns JC

Endothelial Cell Response in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children.
Kim J, Shimizu C, He M, Wang H, Hoffman HM, Tremoulet AH, Shyy JY, Burns JC

Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature.
Jackson HR, Miglietta L, Habgood-Coote D, D'Souza G, Shah P, Nichols S, Vito O, Powell O, Davidson MS, Shimizu C, Agyeman PKA, Beudeker CR, Brengel-Pesce K, Carrol ED, Carter MJ, De T, Eleftheriou I, Emonts M, Epalza C, Georgiou P, De Groot R, Fidler K, Fink C, van Keulen D, Kuijpers T, Moll H, Papatheodorou I, Paulus S, Pokorn M, Pollard AJ, Rivero-Calle I, Rojo P, Secka F, Schlapbach LJ, Tremoulet AH, Tsolia M, Usuf E, Van Der Flier M, Von Both U, Vermont C, Yeung S, Zavadska D, Zenz W, Coin LJM, Cunnington A, Burns JC, Wright V, Martinon-Torres F, Herberg JA, Rodriguez-Manzano J, Kaforou M, Levin M

Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis.
Patel H, Sintou A, Chowdhury RA, Rothery S, Iacob AO, Prasad S, Rainer PP, Martinón-Torres F, Sancho-Shimizu V, Shimizu C, Dummer K, Tremoulet AH, Burns JC, Sattler S, Levin M, DIAMONDS consortium

Implementation of KIDMATCH: A Clinical Decision Support Tool for Diagnosing Pediatric Patients with Multisystem Inflammatory Syndrome and Kawasaki Disease.
Lam JY, Richardson A, Kanegaye JT, Tremoulet AH, Shimizu C, Stadnick NA, Burns JC, Nemati S, Gardiner MA

Multisystem Inflammatory Syndrome therapies in children (MISTIC): A randomized trial.
Jain S, He F, Brown K, Burns JC, Tremoulet AH

Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics.
Menon K, Seo J, Fukazawa R, Ogawa S, Kahn AM, Burns JC, Marsden AL

A New Definition for Multisystem Inflammatory Syndrome in Children.
Son MBF, Burns JC, Newburger JW

Intravenous immunoglobulin resistance in Kawasaki disease patients: prediction using clinical data.
Lam JY, Song MS, Kim GB, Shimizu C, Bainto E, Tremoulet AH, Nemati S, Burns JC

MIS-C: myths have been debunked, but mysteries remain.
Burns JC

Exercise Stress Echocardiography in Kawasaki Disease Patients with Coronary Aneurysms.
Tedla BA, Burns JC, Tremoulet AH, Shimizu C, Gordon JB, El-Said H, Golding F, Davis CK, Dummer KB

Bridging a diagnostic Kawasaki disease classifier from a microarray platform to a qRT-PCR assay.
Kuiper R, Wright VJ, Habgood-Coote D, Shimizu C, Huigh D, Tremoulet AH, van Keulen D, Hoggart CJ, Rodriguez-Manzano J, Herberg JA, Kaforou M, Tempel D, Burns JC, Levin M

Incidence and Severity of Kawasaki Disease Among Vietnamese Children.
Doan NH, Sivilay N, Shimizu C, Nguyen H, Bainto E, Nguyen Q, Tremoulet AH, Burns JC

Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron and Other Variants in Serum From Children With Vaccination-Induced Myocarditis.
Zahra FT, Grubbs G, Dummer K, Tremoulet AH, Shimizu C, Burns JC, Khurana S

Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq.
Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Proekt I, Yu D, Mandel-Brehm C, Wang CY, Miao B, Sowa G, Zorn K, Chan AY, Tagi VM, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kämpe O, Dobbs K, Delmonte OM, Bacchetta R, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL

Single center blind testing of a US multi-center validated diagnostic algorithm for Kawasaki disease in Taiwan.
Kuo HC, Hao S, Jin B, Chou CJ, Han Z, Chang LS, Huang YH, Hwa K, Whitin JC, Sylvester KG, Reddy CD, Chubb H, Ceresnak SR, Kanegaye JT, Tremoulet AH, Burns JC, McElhinney D, Cohen HJ, Ling XB

A machine-learning algorithm for diagnosis of multisystem inflammatory syndrome in children and Kawasaki disease in the USA: a retrospective model development and validation study.
Lam JY, Shimizu C, Tremoulet AH, Bainto E, Roberts SC, Sivilay N, Gardiner MA, Kanegaye JT, Hogan AH, Salazar JC, Mohandas S, Szmuszkovicz JR, Mahanta S, Dionne A, Newburger JW, Ansusinha E, DeBiasi RL, Hao S, Ling XB, Cohen HJ, Nemati S, Burns JC, Pediatric Emergency Medicine Kawasaki Disease Research Group, CHARMS Study Group

Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.
Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S

Publisher Correction: An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease.
Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease.
Shimizu C, Kim J, He M, Tremoulet AH, Hoffman HM, Shyy JY, Burns JC

T Cells in Multisystem Inflammatory Syndrome in Children (MIS-C) Have a Predominant CD4+ T Helper Response to SARS-CoV-2 Peptides and Numerous Virus-Specific CD4- CD8- Double-Negative T Cells.
Hsieh LE, Song J, Grifoni A, Shimizu C, Tremoulet AH, Dummer KB, Burns JC, Sette A, Franco A

Intravenous immunoglobulin induces IgG internalization by tolerogenic myeloid dendritic cells that secrete IL-10 and expand Fc-specific regulatory T cells.
Hsieh LE, Song J, Tremoulet AH, Burns JC, Franco A

Epidemiological and Clinical Features of Kawasaki Disease During the COVID-19 Pandemic in the United States.
Burney JA, Roberts SC, DeHaan LL, Shimizu C, Bainto EV, Newburger JW, Dominguez S, Jone PN, Jaggi P, Szmuszkovicz JR, Rowley AH, Samuy N, Scalici P, Tremoulet AH, Cayan DR, Burns JC, KIDCARE Study Investigators

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

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