Locations

San Diego County

9500 Gilman Dr.
MC 0641
La Jolla, CA 92093-0641

Specialty

Kawasaki Disease

Organization

Rady Children's Specialists of San Diego

Medical Group / IPA

CPMG/RCHN/RCSSD

Medical School

University of North Carolina at Chapel Hill

Residency

Univ of Colorado - Denver

Fellowship

Univ of Colorado - Denver

Board Certifications

Pediatrics

Gender

F

Bio

Dr. Jane C. Burns is the director of the Kawasaki Disease Clinic at Rady Children's Hospital-San Diego and the Kawasaki Disease Research Center at UC San Diego. She is also a professor of pediatrics at UC San Diego School of Medicine.

After earning her medical degree at the University of North Carolina in Chapel Hill in 1978, she completed her pediatric residency and fellowship at the University of Colorado in Denver, followed by additional training in pediatric infectious diseases and molecular virology at Harvard Medical School and Boston Children's Hospital. She joined the faculty at Harvard Medical School in 1986 and moved to San Diego in 1990.

Internationally known for her research on Kawasaki disease (KD), her passion for studying KD has spanned almost three decades, with her first publication in 1982. In addition to her academic pursuits, Dr. Burns is the mother of two daughters. Her husband, John B. Gordon M.D., is an interventional cardiologist who cares for adults with long-term sequelae of KD. Together, working with a team from UC San Diego, they launched the Adult KD Collaborative, a long-range epidemiologic and clinical study of cardiovascular biomarkers and functional studies in adults who suffered from KD in childhood.

Publications

Bridging a diagnostic Kawasaki disease classifier from a microarray platform to a qRT-PCR assay.
Kuiper R, Wright VJ, Habgood-Coote D, Shimizu C, Huigh D, Tremoulet AH, van Keulen D, Hoggart CJ, Rodriguez-Manzano J, Herberg JA, Kaforou M, Tempel D, Burns JC, Levin M

Epidemiological and Clinical Features of Kawasaki Disease During the COVID-19 Pandemic in the United States.
Burney JA, Roberts SC, DeHaan LL, Shimizu C, Bainto EV, Newburger JW, Dominguez S, Jone PN, Jaggi P, Szmuszkovicz JR, Rowley AH, Samuy N, Scalici P, Tremoulet AH, Cayan DR, Burns JC, KIDCARE Study Investigators .

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.
Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S

Long-term health outcomes in young adults after Kawasaki disease.
Daniels LB, Roberts S, Moreno E, Tremoulet AH, Gordon JB, Burns JC

Intravenous immunoglobulin induces IgG internalization by tolerogenic myeloid dendritic cells that secrete IL-10 and expand Fc-specific regulatory T cells.
Hsieh LE, Song J, Tremoulet AH, Burns JC, Franco A

Neutralization of SARS-CoV-2 Omicron and other variants in serum from children with vaccination-induced myocarditis.
Zahra FT, Grubbs G, Dummer K, Tremoulet AH, Shimizu C, Burns JC, Khurana S

Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C.
Burbelo PD, Castagnoli R, Shimizu C, Delmonte OM, Dobbs K, Discepolo V, Lo Vecchio A, Guarino A, Licciardi F, Ramenghi U, Rey-Jurado E, Vial C, Marseglia GL, Licari A, Montagna D, Rossi C, Montealegre Sanchez GA, Barron K, Warner BM, Chiorini JA, Espinosa Y, Noguera L, Dropulic L, Truong M, Gerstbacher D, Mató S, Kanegaye J, Tremoulet AH, Pediatric Emergency Medicine Kawasaki Group., Eisenstein EM, Su HC, Imberti L, Poli MC, Burns JC, Notarangelo LD, Cohen JI

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq.
Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Mandel-Brehm C, Miao B, Sowa G, Zorn K, Chan AY, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kampe O, Dobbs K, Delmonte OM, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL

Multicenter Validation of a Machine Learning Algorithm for Diagnosing Pediatric Patients with Multisystem Inflammatory Syndrome and Kawasaki Disease.
Lam JY, Roberts SC, Shimizu C, Bainto E, Sivilay N, Tremoulet AH, Gardiner MA, Kanegaye JT, Hogan AH, Salazar JC, Mohandas S, Szmuszkovicz JR, Mahanta S, Dionne A, Newburger JW, Ansusinha E, DeBiasi RL, Hao S, Ling XB, Cohen HJ, Nemati S, Burns JC, Pediatric Emergency Medicine Kawasaki Disease Research Group., CHARMS Study Group.

Anakinra Treatment in Patients with Acute Kawasaki Disease with Coronary Artery Aneurysms: A Phase I/IIa Trial.
Yang J, Jain S, Capparelli EV, Best BM, Son MB, Baker A, Newburger JW, Franco A, Printz BF, He F, Shimizu C, Hoshino S, Bainto E, Moreno E, Pancheri J, Burns JC, Tremoulet AH

Global epidemiology of vasculitis.
Watts RA, Hatemi G, Burns JC, Mohammad AJ

Temporal clustering of Kawasaki disease cases around the world.
Burney JA, DeHaan LL, Shimizu C, Bainto EV, Newburger JW, DeBiasi RL, Dominguez SR, Portman MA, Melish M, Bratincsak A, Fabi M, Corinaldesi E, Yu JJ, Gee P, Kitano N, Tremoulet AH, Cayan DR, Burns JC, Kawasaki Disease Climate Study Group.

Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles.
Saper VE, Ombrello MJ, Tremoulet AH, Montero-Martin G, Prahalad S, Canna S, Shimizu C, Deutsch G, Tan SY, Remmers EF, Monos D, Hahn T, Phadke OK, Cassidy E, Ferguson I, Mallajosyula V, Xu J, Rosa Duque JS, Chua GT, Ghosh D, Szymanski AM, Rubin D, Burns JC, Tian L, Fernandez-Vina MA, Mellins ED, Hollenbach JA, Drug Hypersensitivity Consortium., INCHARGE Consortium.

Infliximab versus second intravenous immunoglobulin for treatment of resistant Kawasaki disease in the USA (KIDCARE): a randomised, multicentre comparative effectiveness trial.
Burns JC, Roberts SC, Tremoulet AH, He F, Printz BF, Ashouri N, Jain SS, Michalik DE, Sharma K, Truong DT, Wood JB, Kim KK, Jain S, KIDCARE Multicenter Study Group.

Characterization of SARS-CoV-2 and common cold coronavirus-specific T-cell responses in MIS-C and Kawasaki disease children.
Hsieh LE, Grifoni A, Sidney J, Shimizu C, Shike H, Ramchandar N, Moreno E, Tremoulet AH, Burns JC, Franco A

Biomarkers of inflammation and fibrosis in young adults with history of Kawasaki disease.
Hoshino S, Jain S, Shimizu C, Roberts S, He F, Daniels LB, Kahn AM, Tremoulet AH, Gordon JB, Burns JC

Computational modeling of blood component transport related to coronary artery thrombosis in Kawasaki disease.
Grande Gutiérrez N, Alber M, Kahn AM, Burns JC, Mathew M, McCrindle BW, Marsden AL

Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C.
Zhu YP, Shamie I, Lee JC, Nowell CJ, Peng W, Angulo S, Le LN, Liu Y, Miao H, Xiong H, Pena CJ, Moreno E, Griffis E, Labou SG, Franco A, Broderick L, Hoffman HM, Shimizu C, Lewis NE, Kanegaye JT, Tremoulet AH, Burns JC, Croker BA, Pediatric Emergency Medicine Kawasaki Disease Research Group Consortium.

Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome.
Wang WT, He M, Shimizu C, Croker BA, Hoffman HM, Tremoulet AH, Burns JC, Shyy JY

Hyponatremia in Patients With Multisystem Inflammatory Syndrome in Children.
Mills T, Trivedi A, Tremoulet AH, Hershey D, Burns JC

Kawasaki Disease Patient Stratification and Pathway Analysis Based on Host Transcriptomic and Proteomic Profiles.
Jackson H, Menikou S, Hamilton S, McArdle A, Shimizu C, Galassini R, Huang H, Kim J, Tremoulet A, Thorne A, Fischer R, de Jonge MI, Kuijpers T, Wright V, Burns JC, Casals-Pascual C, Herberg J, Levin M, Kaforou M, On Behalf Of The Perform Consortium

An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease.
Sahoo D, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye J, Pediatric Emergency Medicine Kawasaki Disease Research Group., Bocchini J, Das S, Burns JC, Ghosh P

Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease.
Hoggart C, Shimizu C, Galassini R, Wright VJ, Shailes H, Bellos E, Herberg JA, Pollard AJ, O'Connor D, Choi SW, Seaby EG, Menikou S, Hibberd M, Sallah N, Burgner D, Brogan P, Patel H, Kim J, Tremoulet AH, Salo E, van Stijn D, Kuijpers T, Burns JC, Levin M, International Kawasaki Disease Genetics Consortium., UK Kawasaki Disease Genetics Consortium., EUCLIDS Consortium.

Mistaken MIS-C: A Case Series of Bacterial Enteritis Mimicking MIS-C.
Dworsky ZD, Roberts JE, Son MBF, Tremoulet AH, Newburger JW, Burns JC

Characterization of the T Cell Response to Lactobacillus casei Cell Wall Extract in Children With Kawasaki Disease and Its Potential Role in Vascular Inflammation.
Hsieh LE, Tremoulet AH, Burns JC, Noval Rivas M, Arditi M, Franco A

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

PubMed is a third-party website and not affiliated with Rady Children's Hospital-San Diego.

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