Research & Clinical Trials

Neonatal cooling blanket

Neonatal cooling blanket

Our neonatologists are actively involved in clinical research to improve the outcomes of critically ill neonates.

Recently, our division participated in multicenter study testing a therapeutic cooling blanket on newborns with hypoxic ischemic encephalopathy (HIE), a major cause of death and severe disability. The cooling blanket was used during transport to the hospital.

The study found that the cooling blanket, compared to the standard practice, enabled more infants to achieve their target temperature. As a result, both the survival and neurodevelopmental outcomes in newborns with HIE could be significantly improved.

The study was published in the April 2015 issue of the Journal of Pediatrics. Click here for the abstract.

In other research, we are:

  • Evaluating anti-convulsant medications that limit seizures.
  • Testing the effectiveness of a wireless EEG, a stamp-sized wearable patch of tiny circuits, sensors and wireless transmitters that sticks to the skin like a temporary tattoo. It would replace all the wires that are currently used to monitor infants.

Among our previous research:

  • We participated in the study, “Inhaled Nitric Oxide for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants.”
  • We collaborated with The Neurosciences Institute in San Diego to evaluate the effects of different interventions, including music, on physiological measures of stress in neonates.
  • We concluded a multi-center study evaluating the use of Plavix and aspirin to decrease thrombosis in postoperative heart patients with systemic pulmonary shunts.

For more information on our research, visit the UC San Diego Department of Pediatrics website.