Kate’s rare disease was finally diagnosed and successfully treated by  Dr. Hal Hoffman. Read her remarkable story.

The Allergy & Immunology Program of Rady Children’s Specialists of San Diego provides comprehensive care for children with allergic immune disorders, conducts cutting-edge research and is actively involved in professional organizations that advance treatment and research in the field.

Our Asthma & Allergy Clinic is offered at Rady Children’s Hospital-San Diego and satellite offices in San Diego and Riverside counties. At the Hospital, we also offer specialized clinics for immunology, food allergy, severe asthmaeosinophilic gastrointestinal disorders and recurrent fever disorders. The latter two clinics were the first of their kind in the western United States.

Our Food Allergy Center is directed by Stephanie Leonard, M.D., who trained at Mt. Sinai Hospital under the tutelage of Hugh Sampson, M.D., one of the world’s foremost authorities on food allergies. Dr. Leonard has also published research in the emerging science of food desensitization and induction of tolerance.

Research and clinical trials are a major focus of our Division and have led to the development of promising treatments.

Additionally, our specialists have multiple roles in local and national organizations, with the goal of improving the lives of children with allergy & immunology disorders. These organizations include the Academy of Allergy, Asthma & Immunology, American Lung Foundation (through the Asthma Camp), The Food Allergy & Anaphylaxis Network, and American Partnership for Eosinophilic Disorders.

Video: Dr. Hal Hoffman discusses the Allergy & Immunology program

Division Achievements:

  • Kids Find Breathing Room at Asthma, Camp California Healthline, features Michael Welch, M.D.
  • Children Outgrow Food Allergies: You Need to Retest, MedShadow.org, features Stephanie Leonard, M.D.
  • Seema Aceves, M.D., Ph.D., is the senior author on published international guidelines for the diagnosis of eosinophilic esophagitis in adults and children.
  • Seema Aceves, M.D., Ph.D.John Bastian, M.D., and Ranjan Dohil, M.D., (Gastroenterology) created a novel steroid formulation to treat eosinophilic esophagitis (EoE). Recently, a ready-to-use formulation was developed and is now being studied in its second national clinical trial in both children and adults. It is the hope that these clinical trials will result in the first Food and Drug Administration-approved EoE therapy. Learn more.
  • Hal Hoffman, M.D., co-discovered the gene for a cold urticaria (hives) syndrome that he originally described. His findings were published in The New England Journal of Medicine.  The identification of this gene led to further discoveries and a novel treatment of cryopyrin-associated periodic syndromes (CAPS). This treatment is now the first line and most effective therapy for these previously untreatable diseases.
  • Anthony Horner, M.D., published work identifying a novel role for house dust in the activation of NKT (natural killer T) cells, which are important in development of airway inflammation. This work was featured on the cover of the Journal of Experimental Medicine and reviewed in the Journal of Asthma Allergy and Clinical Immunology.

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