Publications & Researchers

ADI Researchers:

Publications (by Autism Discovery Institute Staff and Research Partners)

Note: Bolded authors are affiliated with the Autism Discovery Institute, Rady Children’s Institute for Genomic Medicine and the Comprehensive Autism and Neurodevelopmental Disorders (CANDo) program, or the Child & Adolescent Services Research Center (CASRC)

2019 (January – June)

Neurobiological Research

Wigby K, Nicolas S, Carpinello M, Ricciardi MT, Willis MJ. Whole Exome Sequencing Guides Pharmacotherapy for an Adolescent With Autism Spectrum Disorder and Psychosis. J Am Acad Child Adolesc Psychiatry. 2019 Mar, 58(3):376-377. https://doi.org/10.1016/j.jaac.2018.09.432

Screening and Assessment

Pierce K, Gazestani VH, Bacon E, Barnes CC, Cha D, Nalabolu S, Lopez L, Moore A, Pence-Stophaeros S, Courchesne E. Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months. JAMA Pediatrics. 2019 April 29. https://doi.org/10.1001/jamapediatrics.2019.0624

Bacon EC, Osuna S, Courchesne E, Pierce K. Naturalistic language sampling to characterize the language abilities of 3-year-olds with autism spectrum disorder. Autism 2019 April; 23(3): 699-712. https://doi.org/10.1177/1362361318766241

Psychosocial Intervention, Services, and Implementation Research

Stahmer AC, Suhrheinrich J, Roesch S, Zeedyk SM, Wang T, Chan N, Lee HS. Examining relationships between child skills and potential key components of an evidence-based practice in ASD. Res Dev Disabil. 2019, April 25. https://doi.org/10.1016/j.ridd.2019.04.003

Stadnick NA, Brookman-Frazee L, Mandell DS, Kuelbs CL, Coleman KJ, Sahms T, Aarons GA. A mixed methods study to adapt and implement integrated mental healthcare for children with autism spectrum disorder. Pilot Feasibility Study. 2019 Mar 28;5:51. https://doi.org/10.1186/s40814-019-0434-5

Stadnick NA, Meza RD, Suhrheinrich J, Aarons GA, Brookman-Frazee L, Lyon AR, Mandell DS, Locke J. Leadership profiles associated with the implementation of behavioral health evidence-based practices for autism spectrum disorder in schools. Autism. 2019 Mar 27:1362361319834398. https://doi.org/10.1177/1362361319834398

Brookman-Frazee L, Chlebowski C, Suhrheinrich J, Finn N, Dickson KS, Aarons GA, Stahmer A. Characterizing Shared and Unique Implementation Influences in Two Community Services Systems for Autism: Applying the EPIS Framework to Two Large-Scale Autism Intervention Community Effectiveness Trials. Adm Policy Ment Health. 2019 Mar 23. https://doi.org/10.1007/s10488-019-00931-4

Maddox BB, Rump KM, Stahmer AC, Suhrheinrich J, Rieth SR, Nahmias AS, Nuske HJ, Reisinger EM, Crabbe SR, Bronstein B, Mandell DS. Concordance between a U.S. Educational Autism Classification and the Autism Diagnostic Observation Schedule. J Clin Child Adolesc Psychol. 2019 Mar 20:1-7. https://doi.org/10.1080/15374416.2019.1567345

Brookman-Frazee L, Roesch S, Chlebowski C, Baker-Ericzen M, Ganger W. Effectiveness of Training Therapists to Deliver An Individualized Mental Health Intervention for Children With ASD in Publicly Funded Mental Health Services: A Cluster Randomized Clinical Trial. JAMA Psychiatry. 2019 Mar 6. https://doi.org/10.1001/jamapsychiatry.2019.0011

Bishop-Fitzpatrick L, Dababnah S, Baker-Ericzén MJ, Smith MJ, Magaña SM. Autism spectrum disorder and the science of social work: A grand challenge for social work research. Soc Work Ment Health, 17(1), 73-92. https://doi.org/10.1080/15332985.2018.1509411

Dyson MW, Chlebowski C, Brookman-Frazee L. Therapists’ Adaptations to an Intervention to Reduce Challenging Behaviors in Children with Autism Spectrum Disorder in Publicly Funded Mental Health Services. J Autism Dev Disord. 2019 Mar;49(3):924-934. https://doi.org/10.1007/s10803-018-3795-3

Locke J, Lawson GM, Beidas RS, Aarons GA, Xie M, Lyon AR, Stahmer A, Seidman M, Frederick L, Oh C, Spaulding C, Dorsey S, Mandell DS. Individual and organizational factors that affect implementation of evidence-based practices for children with autism in public schools: a cross-sectional observational study. Implement Sci. 2019 Mar 13;14(1):29. https://doi.org/10.1186/s13012-019-0877-3

Williams NJ, Frank HE, Frederick L, Beidas RS, Mandell DS, Aarons GA, Green P, Locke J. Organizational culture and climate profiles: relationships with fidelity to three evidence-based practices for autism in elementary schools. Implement Sci. 2019 Feb 12;14(1):15. https://doi.org/10.1186/s13012-019-0863-9

2018

Neurobiological Research

Raznahan A, Parikshak NN, Chandran V, Blumenthal JD, Clasen LS, Alexander-Bloch AF, Zinn AR, Wangsa D, Wise J, Murphy DGM, Bolton PF, Ried T, Ross J, Giedd JN, Geschwind DH. Sex-chromosome dosage effects on gene expression in humans. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7398-7403. https://doi.org/10.1073/pnas.1802889115

Clark MM, Stark Z, Farnaes L, Tan TY, White SM, Dimmock D, Kingsmore SF. Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases. NPJ Genom Med. 2018 Jul 9;3:16.

Brandler WM, Antaki D, Gujral M, Kleiber ML, Whitney J, Maile MS, Hong O, Chapman TR, Tan S, Tandon P, Pang T, Tang SC, Vaux KK, Yang Y, Harrington E, Juul S, Turner DJ, Thiruvahindrapuram B, Kaur G, Wang Z, Kingsmore SF, Gleeson JG, Bisson D, Kakaradov B, Telenti A, Venter JC, Corominas R, Toma C, Cormand B, Rueda I, Guijarro S, Messer KS, Nievergelt CM, Arranz MJ, Courchesne E, Pierce K, Muotri AR, Iakoucheva LM, Hervas A, Scherer SW, Corsello C, Sebat J. Paternally inherited cis-regulatory structural variants are associated with autism. Science. 2018 Apr 20;360(6386):327-331. https://doi.org/ 10.1126/science.aan2261

Russo FB, Freitas BC, Pignatari GC, Fernandes IR, Sebat J, Muotri AR, Beltrão-Braga PCB. Modeling the Interplay Between Neurons and Astrocytes in Autism Using Human Induced Pluripotent Stem Cells. Biol Psychiatry. 2018 Apr 1;83(7):569-578. https://doi.org/10.1016/j.biopsych.2017.09.021

Johannesen KM, Gardella E, Linnankivi T, Courage C, de Saint Martin A, Lehesjoki AE, Mignot C, Afenjar A, Lesca G, Abi-Warde MT, Chelly J, Piton A, Merritt JL 2nd, Rodan LH, Tan WH, Bird LM, Nespeca M, Gleeson JG, Yoo Y, Choi M, Chae JH, Czapansky-Beilman D, Reichert SC, Pendziwiat M, Verhoeven JS, Schelhaas HJ, Devinsky O, Christensen J, Specchio N, Trivisano M, Weber YG, Nava C, Keren B, Doummar D, Schaefer E, Hopkins S, Dubbs H, Shaw JE, Pisani L, Myers CT, Tang S, Tang S, Pal DK, Millichap JJ, Carvill GL, Helbig KL, Mecarelli O, Striano P, Helbig I, Rubboli G, Mefford HC, Møller RS. Defining the phenotypic spectrum of SLC6A1 mutations. Epilepsia. 2018 Feb;59(2):389-402. https://doi.org/10.1111/epi.13986

Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG. A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features. J Med Genet. 2018 Jan;55(1):48-54. https://doi.org/10.1136/jmedgenet-2017-104627

Psychosocial Intervention, Services and Implementation Research

Dyson MW, Chlebowski C, Brookman-Frazee L. Therapists’ Adaptations to an Intervention to Reduce Challenging Behaviors in Children with Autism Spectrum Disorder in Publicly Funded Mental Health Services. J Autism Dev Disord. 2018 Oct27. https://doi.org/10.1007/s10803-018-3795-3

Chlebowski C, Magaña S, Wright B, Brookman-Frazee L. Implementing an intervention to address challenging behaviors for autism spectrum disorder in publicly-funded mental health services: Therapist and parent perceptions of delivery with Latinx families. Cultur Divers Ethnic Minor Psychol. 2018 Jul 19. https://doi.org/10.1037/cdp0000215

Brookman-Frazee L, Stahmer AC. Effectiveness of a multi-level implementation strategy for ASD interventions: study protocol for two linked cluster randomized trials. Implement Sci. 2018 May 9;13(1):66. https://doi.org/10.1186/s13012-018-0757-2

Stahmer AC, Suhrheinrich J, Schetter PL, McGee Hassrick E. Exploring multi-level system factors facilitating educator training and implementation of evidence-based practices (EBP): a study protocol. Implement Sci. 2018 Jan 8;13(1):3. https://doi.org/10.1186/s13012-017-0698-1

Dickson KS, Suhrheinrich J, Rieth SR, Stahmer AC. Parent and Teacher Concordance of Child Outcomes for Youth with Autism Spectrum Disorder. J Autism Dev Disord. 2018 May;48(5):1423-1435. https://doi.org/10.1007/s10803-017-3382-z

Rieth SR, Haine-Schlagel R, Burgeson M, Searcy K, Dickson KS, Stahmer AC. Integrating a Parent-Implemented Blend of Developmental and Behavioral Intervention Strategies into Speech-Language Treatment for Toddlers at Risk for Autism Spectrum Disorder. Semin Speech Lang. 2018 Apr;39(2):114-124. https://doi.org/10.1055/s-0038-1627483

Baker-Ericzén MJ, Brookman-Frazee L, Brodkin ES. Accelerating research on treatment and services for transition age youth and adults on the autism spectrum. Autism. 2018 Jan;22(1):2-5. https://doi.org/10.1177/1362361317738646

Baker-Ericzén MJ, Fitch MA, Kinnear M, Jenkins MM, Twamley EW, Smith L, Montano G, Feder J, Crooke PJ, Winner MG, Leon J. Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study. Autism. 2018 Jan;22(1):6-19. https://doi.org/10.1177/1362361317724294

Mazurek MO, Carlson C, Baker-Ericzén M, Butter E, Norris M, Kanne S. Construct Validity of the Autism Impact Measure (AIM). J Autism Dev Disord. 2018 Jan 17.  https://doi.org/10.1007/s10803-018-3462-8

Kerns CM, Moskowitz LJ, Rosen T, Drahota A, Wainer A, Josephson AR, Soorya L, Cohn E, Chacko A, Lerner MD. A Multisite, Multidisciplinary Delphi Consensus Study Describing “Usual Care” Intervention Strategies for School-Age to Transition-Age Youth With Autism. J Clin Child Adolesc Psychol. 2019;48(sup1):S247-S268. https://doi.org/10.1080/15374416.2017.1410826

2017

Neurobiological Research

Meerschaut I, Rochefort D, Revençu N, Pètre J, Corsello C, Rouleau GA, Hamdan  FF, Michaud JL, Morton J, Radley J, Ragge N, García-Miñaúr S, Lapunzina P, Bralo  MP, Mori MÁ, Moortgat S, Benoit V, Mary S, Bockaert N, Oostra A, Vanakker O, Velinov M, de Ravel TJ, Mekahli D, Sebat J, Vaux KK, DiDonato N, Hanson-Kahn AK,  Hudgins L, Dallapiccola B, Novelli A, Tarani L, Andrieux J, Parker MJ, Neas K, Ceulemans B, Schoonjans AS, Prchalova D, Havlovicova M, Hancarova M, Budisteanu M, Dheedene A, Menten B, Dion PA, Lederer D, Callewaert B. FOXP1-related intellectual disability syndrome: a recognisable entity. J Med Genet. 2017 Sep;54(9):613-623. https://doi.org/10.1136/jmedgenet-2017-104579

Pagel KA, Pejaver V, Lin GN, Nam HJ, Mort M, Cooper DN, Sebat J, Iakoucheva LM, Mooney SD, Radivojac P. When loss-of-function is loss of function: assessing mutational signatures and impact of loss-of-function genetic variants.Bioinformatics. 2017 Jul 15;33(14):i389-i398. https://doi.org/10.1093/bioinformatics/btx272

Wallace GL, Dudley K, Anthony L, Pugliese CE, Orionzi B, Clasen L, Lee NR, Giedd JN, Martin A, Raznahan A, Kenworthy L. Divergence of Age-Related Differences in Social-Communication: Improvements for Typically Developing Youth but Declines for Youth with Autism Spectrum Disorder. J Autism Dev Disord. 2017 Feb;47(2):472-479. https://doi.org/10.1007/s10803-016-2972-5

Marshall CR… Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017 Jan;49(1):27-35. https://doi.org/10.1038/ng.3725

Psychosocial Intervention, Services and Implementation Research

Brookman-Frazee L, Stadnick N, Chlebowski C, Baker-Ericzén M, Ganger W. Characterizing psychiatric comorbidity in children with autism spectrum disorder receiving publicly funded mental health services. Autism. 2017 Sep 1:1362361317712650. https://doi.org/10.1177/1362361317712650

Blake JM, Rubenstein E, Tsai PC, Rahman H, Rieth SR, Ali H, Lee LC. Lessons learned while developing, adapting and implementing a pilot parent-mediated behavioural intervention for children with autism spectrum disorder in rural Bangladesh. Autism. 2017 Jul;21(5):611-621. https://doi.org/10.1177/1362361316683890

Stadnick N, Chlebowski C, Brookman-Frazee L. Caregiver-Teacher Concordance of Challenging Behaviors in Children with Autism Spectrum Disorder Served in Community Mental Health Settings. J Autism Dev Disord. 2017 Jun;47(6):1780-1790. https://doi.org/10.1007/s10803-017-3101-9

Stadnick N, Chlebowski C, Baker-Ericzén M, Dyson M, Garland A, Brookman-Frazee L. Psychiatric comorbidity in autism spectrum disorder: Correspondence between mental health clinician report and structured parent interview. Autism. 2017 Oct;21(7):841-851. https://doi.org/10.1177/1362361316654083

Stahmer AC, Brookman-Frazee L, Rieth SR, Stoner JT, Feder JD, Searcy K, Wang. Parent perceptions of an adapted evidence-based practice for toddlers with autism in a community setting. Autism. 2017 Feb;21(2):217-230. https://doi.org/10.1177/1362361316637580

Stahmer, A. C., Aranbarri, A., Drahota, A., & Rieth, S. Toward a more collaborative research culture: Extending translational science from research to community and back again. Autism. 2017

Suhrheinrich, J., & Chan, J. Exploring the effect of immediate video feedback on coaching. Journal of Special Education Technology, 2017 32(1), 47-53.

Drahota, A., Chlebowski, C., Stadnick, N., Baker-Ericzen, M., & Brookman-Frazee, L. (2017). Dissemination and implementation of behavioral treatments for anxiety in ASD. In C. Kerns, E. Storch, P. Kendall, J.J. Wood, & P. Renno (Eds.), Evidence Based Assessment And Treatment Of Anxiety In Children And Adolescents With Autism Spectrum Disorder. Elsevier.

Koegel, R.L., Koegel, L.K. Vernon, T., & Brookman-Frazee, L. (2017).  Pivotal response training for autism spectrum disorder.  In A.E. Kazdin and J. Weisz (Eds.) Evidenced-Based Psychotherapies for Children & Adolescents.  New York: Guilford Publications.