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Rady Children's Specialists

Tuberous Sclerosis Complex (TSC) Clinic

Tuberous sclerosis complex (TSC), a genetic disorder that affects 1 in 5,000 individuals, can affect many organs in the body, including the brain, heart, kidneys, lungs, and skin. TSC is a lifelong genetic disorder and condition in which complications and symptoms can arise at any time for patients. The most effective means of providing treatment and medical/clinical care that benefits each individual child is to use a team approach at the tuberous sclerosis complex clinic.

Established in 2015, the TSC Clinic brings together various specialists in one location so that TSC patients can be cared for and seen by several specialists in a single visit. This tuberous sclerosis complex center treats and follows children into adulthood. Team members for TSC patients include a pediatric neurologist, nurse manager, pediatric cardiologist, pediatric nephrologist, pediatric pulmonologist and pediatric neuro-oncologist, as well as specialists in pediatric ophthalmology, psychology, dermatology and neurosurgery. The clinic has been approved as a TSC Center by the Tuberous Sclerosis Alliance, a national organization that fosters education, awareness and research on the genetic disorder/condition.

Tuberous Sclerosis Complex Clinic Team

Our multidisciplinary TSC Clinic team includes:

Anuja Jindal, M.D., M.P.H., Director; Pediatric neurologist and specialist in neurodevelopmental disabilities

Marsha Harp, R.N., Nurse manager

Maria Coronel, Administrative Coordinator

Beth Printz, M.D., Pediatric cardiologist

Peter Yorgin, M.D, Pediatric nephrologist

Jessica Sprague, M.D., Pediatric dermatologist

Sophia Ceulemans, M.S., LCGC, Genetic counselor

Jazlyn Alameda, Social worker

Research

Research is an important part of the TSC Clinic, with a focus on developing a better understanding of TSC and how to treat it with clinical care, including for children. It has been one of the study sites for a multicenter trial of the drug everolimus for the treatment of intractable epilepsy in TSC and continues to participate in the long-term follow-up phase of the study. The tuberous sclerosis complex center is also exploring basic science opportunities related to the m-TOR cellular pathway and collaborates with other TSC centers around the country.